In enzymology, a L-arabinitol 4-dehydrogenase (EC 1.1.1.12) is an enzyme that catalyzes the chemical reaction
| L-arabinitol 4-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 L-arabinitol 4-dehydrogenase homotetramer, Neurospora crassa | |||||||||
| Identifiers | |||||||||
| EC no. | 1.1.1.12 | ||||||||
| CAS no. | 9028-19-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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- L-arabinitol NAD L-xylulose NADH H
Thus, the two substrates of this enzyme are L-arabinitol and NAD , whereas its 3 products are L-xylulose, NADH, and H .
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is L-arabinitol:NAD 4-oxidoreductase (L-xylulose-forming). Other names in common use include pentitol-DPN dehydrogenase, and L-arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.
References
edit- Chiang C, Knight SG (1960). "A new pathway of pentose metabolism". Biochem. Biophys. Res. Commun. 3 (5): 554–9. doi:10.1016/0006-291X(60)90174-1. PMID 13692998.554-9&rft.date=1960&rft_id=info:doi/10.1016/0006-291X(60)90174-1&rft_id=info:pmid/13692998&rft.aulast=Chiang&rft.aufirst=C&rft.au=Knight, SG&rfr_id=info:sid/en.wikipedia.org:L-arabinitol 4-dehydrogenase" class="Z3988">
- Chiang C, Knight SG (1961). "L-Arabinose metabolism by cell-free extracts of Penicillium chrysogenum". Biochim. Biophys. Acta. 46 (2): 271–8. doi:10.1016/0006-3002(61)90750-8. PMID 13692999.271-8&rft.date=1961&rft_id=info:doi/10.1016/0006-3002(61)90750-8&rft_id=info:pmid/13692999&rft.aulast=Chiang&rft.aufirst=C&rft.au=Knight, SG&rfr_id=info:sid/en.wikipedia.org:L-arabinitol 4-dehydrogenase" class="Z3988">
