Jayant Bhalchandra Udgaonkar (Marathi: Jayanta Udgāṁvakara) is a molecular biologist studying the processes by which a random chain of amino acids stabilises into a functional structure during or after translation.[1][2]

Jayant B. Udgaonkar
Jayanta Udgāṁvakara
Born (1960-03-22) March 22, 1960 (age 64)
Maharashtra
EducationIIT Madras (MSc) Cornell University (PhD)
Alma materSt. Xavier's College, Mumbai (BSc)
Organization(s)National Centre for Biological Sciences, IISER Pune
Known forProtein-folding
Websitesites.google.com/acads.iiserpune.ac.in/prof-udgaonkar-lab

Early Life and Education

Born on 22 March 1960 to Bhalchandra Udgaonkar, a theoretical physicist, and Suhasini Udgaonkar, a renowned historian, Jayant Udgaonkar studied Chemistry at St. Xavier's College, Mumbai (BSc, 1979) and IIT Madras (MSc, 1981), and Biochemistry at Cornell University.[2][3][4]

Protein Folding

While studying the kinetics of acetylcholine receptors in response to the binding of ACh at Stanford University, he was struck by the structural precision of protein molecules that enabled them to perform highly specialized tasks with extreme precision. Consequently, he focused his attention on the processes that make these structures possible, and what may go wrong in these highly accurate processes. In one of his earliest studies, he found that a certain hydrophobic collapse is the first stage in a typical protein folding process. His current work focuses on the formation of amyloids.[5][6]

Awards and Honors

Selected bibliography

  • Jayant B Udgaonkar, Robert L Baldwin (November 1990). "Early folding intermediate of ribonuclease A." Proceedings of the National Academy of Sciences. 87 (21): 8197–8201. Bibcode:1990PNAS...87.8197U. doi:10.1073/pnas.87.21.8197. PMC 54922. PMID 2236032.8197-8201&rft.date=1990-11&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC54922#id-name=PMC&rft_id=info:pmid/2236032&rft_id=info:doi/10.1073/pnas.87.21.8197&rft_id=info:bibcode/1990PNAS...87.8197U&rft.au=Jayant B Udgaonkar, Robert L Baldwin&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC54922&rfr_id=info:sid/en.wikipedia.org:Jayant B. Udgaonkar" class="Z3988">

References

  1. ^ "Jayant B. Udgaonkar - IISER Pune".
  2. ^ a b "Felicitation Event Honouring Prof. Jayant B. Udgaonkar at IISER Pune".
  3. ^ Phondke, Bal; Sheth, Parul R.; Naik-Satam, Suhas; Deshpande, A.P. (2007). B.M. Udgaonkar: Eminent Scientist and Educationist (PDF). Mumbai: National Center for Science Communication; Homi Bhabha Centre for Science Communication.
  4. ^ a b "Profile on NCBS" (PDF). National Centre for Biological Sciences. 2016. Retrieved 15 October 2016.
  5. ^ "Jayant Udgaonkar on Google Scholar". Author profile. Google Scholar. 2016. Retrieved 16 October 2016.
  6. ^ "Jayant Udgaonkar on ResearchGate". Author profile. 2016. Retrieved 16 October 2016.
  7. ^ "Rashtriya Vigyan Puraskar (RVP) - 2024 : Final List of Awardees" (PDF). awards.gov.in. CASU, Ministry of Home Affairs, Government of India. Retrieved 15 August 2024.
  8. ^ "Rashtriya Vigyan Puraskar: Chandrayaan-3 team and 32 others selected for first ever edition". The Economic Times. 7 August 2024. Retrieved 15 August 2024.