Itaconyl-CoA hydratase

The enzyme itaconyl-CoA hydratase (EC 4.2.1.56) catalyzes the chemical reaction

itaconyl-CoA hydratase
Identifiers
EC no.4.2.1.56
CAS no.37290-83-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
citramalyl-CoA itaconyl-CoA H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is citramalyl-CoA hydro-lyase (itaconyl-CoA-forming). Other names in common use include itaconyl coenzyme A hydratase, and citramalyl-CoA hydro-lyase. This enzyme participates in c5-branched dibasic acid metabolism.

References

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  • Cooper RA, Kornberg HL (1964). "The utilization of itaconate by Pseudomonas sp". Biochem. J. 91 (1): 82–91. PMC 1202819. PMID 4284209.82-91&rft.date=1964&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1202819#id-name=PMC&rft_id=info:pmid/4284209&rft.aulast=Cooper&rft.aufirst=RA&rft.au=Kornberg, HL&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1202819&rfr_id=info:sid/en.wikipedia.org:Itaconyl-CoA hydratase" class="Z3988">