In enzymology, a hydroxyphenylpyruvate reductase (EC 1.1.1.237) is an enzyme that catalyzes the chemical reaction
| hydroxyphenylpyruvate reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.237 | ||||||||
| CAS no. | 117590-77-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- 3-(4-hydroxyphenyl)lactate NAD 3-(4-hydroxyphenyl)pyruvate NADH H
Thus, the two substrates of this enzyme are 3-(4-hydroxyphenyl)lactate and NAD , whereas its 3 products are 3-(4-hydroxyphenyl)pyruvate, NADH, and H .
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is 4-hydroxyphenyllactate:NAD oxidoreductase. This enzyme is also called HPRP. This enzyme participates in tyrosine metabolism and phenylalanine metabolism.
References
edit- Petersen M, Alfermann AW (1988). "Two new enzymes of rosmarinic acid biosynthesis from cell cultures of Coleus blumei: hydroxyphenylpyruvate reductase and rosmarinic acid synthase". Z. Naturforsch. C: Biosci. 43: 501–504.501-504&rft.date=1988&rft.aulast=Petersen&rft.aufirst=M&rft.au=Alfermann, AW&rfr_id=info:sid/en.wikipedia.org:Hydroxyphenylpyruvate reductase" class="Z3988">
