Hokovirus (HokV) is a genus of giant double-stranded DNA-containing viruses (NCLDV). This genus was detected during the analysis of metagenome samples of bottom sediments of reservoirs at the wastewater treatment plant in Klosterneuburg, Austria. New Klosneuvirus (KNV), Catovirus and Indivirus genera (all found in these sewage waters) were also described together with Hokovirus, building up a putative virus subfamily Klosneuvirinae (Klosneuviruses) with KNV as type genus.[1] Hokovirus has a large genome of 1.33 million base pairs (881 gene families). This is the third largest genome among known Klosneuviruses after KNV (1.57 million base pairs, 1272 gene families) and Catovirus. GC content is 21.4 %[1] Classification of metagenome, made by analyzing 18S rRNA indicate that their hosts are relate to the simple Cercozoa.[1]
| Hokovirus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Varidnaviria |
| Kingdom: | Bamfordvirae |
| Phylum: | Nucleocytoviricota |
| Class: | Megaviricetes |
| Order: | Imitervirales |
| Family: | Mimiviridae |
| Subfamily: | Klosneuvirinae |
| Genus: | Hokovirus |
Phylogenetic tree topology of Mimiviridae is still under discussion. Some authors (CNS 2018) like to put Klosneuviruses together with Cafeteria roenbergensis virus (CroV) and Bodo saltans virus (BsV) into a tentative subfamily called Aquavirinae.[2] Another proposal is to put them together with Mimiviruses into a subfamily Megavirinae.[3]
See also
editReferences
edit- ^ a b c Schulz, Frederik; Yutin, Natalya; Ivanova, Natalia N.; Ortega, Davi R.; Lee, Tae Kwon; Vierheilig, Julia; Daims, Holger; Horn, Matthias; Wagner, Michael (2017-04-07). "Giant viruses with an expanded complement of translation system components". Science. 356 (6333): 82–85. Bibcode:2017Sci...356...82S. doi:10.1126/science.aal4657. ISSN 0036-8075. PMID 28386012.
- ^ Centre national de la recherche scientifique (CNS): List of the main “giant” viruses known as of today, Université Aix Marseille, 18. April 2018
- ^ Deeg, C.M.; Chow, E.C.T.; Suttle, C.A. (2018). "The kinetoplastid-infecting Bodo saltans virus (BsV), a window into the most abundant giant viruses in the sea". eLife. 7: e33014. doi:10.7554/eLife.33014. PMC 5871332. PMID 29582753.
Further reading
edit- Mitch Leslie: Giant viruses found in Austrian sewage fuel debate over potential fourth domain of life. In: Science. 5. April 2017, doi:10.1126/science.aal1005.