In molecular biology, the hepatitis A virus cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase in hepatitis A virus (HAV). It is larger than the CREs found in related Picornavirus species, but is thought to be functionally similar. It is thought to be involved in uridylylation of VPg.[1]
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edit- ^ Yang, Y; Yi, M; Evans, DJ; Simmonds, P; Lemon, SM (October 2008). "Identification of a conserved RNA replication element (cre) within the 3Dpol-coding sequence of hepatoviruses". Journal of Virology. 82 (20): 10118–28. doi:10.1128/jvi.00787-08. PMC 2566277. PMID 18684812.10118-28&rft.date=2008-10&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566277#id-name=PMC&rft_id=info:pmid/18684812&rft_id=info:doi/10.1128/jvi.00787-08&rft.aulast=Yang&rft.aufirst=Y&rft.au=Yi, M&rft.au=Evans, DJ&rft.au=Simmonds, P&rft.au=Lemon, SM&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566277&rfr_id=info:sid/en.wikipedia.org:Hepatitis A virus cis-acting replication element" class="Z3988">