HIE-124

HIE-124
Identifiers
	IUPAC name Ethyl 8-oxo-6,7-dihydro-5H-[1,3]thiazolo[3,2-a][1,3]diazepine-3-carboxylate;
CAS Number	805326-00-5;
PubChem CID	11447815;
ChemSpider	9622668;
UNII	JS6A6EQZ44;
ChEMBL	ChEMBL450014;
Chemical and physical data
Formula	C10H12N2O3S
Molar mass	240.28 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(C1=CSC(N1CCC2)=NC2=O)OCC;
	InChI InChI=1S/C10H12N2O3S/c1-2-15-9(14)7-6-16-10-11-8(13)4-3-5-12(7)10/h6H,2-5H2,1H3; Key:UXGPDPNGDCOQBY-UHFFFAOYSA-N;

HIE-124 is an investigational nonbenzodiazepine drug being researched for its short acting hypnotic effects.^[1]

References

^ Kadi A, El-Kashef H, Abdel-Aziz A, Hassan G, Tettey J, Grant M, Lehmann J, El-Subbagh H (February 2008). "Synthesis, ultra-short acting hypnotic activity, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a] [1,3]diazepin-3-carboxylate (HIE-124)". Archiv der Pharmazie. 341 (2): 81–89. doi:10.1002/ardp.200700132. PMID 18214840. S2CID 12263886.81-89&rft.date=2008-02&rft_id=https://api.semanticscholar.org/CorpusID:12263886#id-name=S2CID&rft_id=info:pmid/18214840&rft_id=info:doi/10.1002/ardp.200700132&rft.aulast=Kadi&rft.aufirst=A&rft.au=El-Kashef, H&rft.au=Abdel-Aziz, A&rft.au=Hassan, G&rft.au=Tettey, J&rft.au=Grant, M&rft.au=Lehmann, J&rft.au=El-Subbagh, H&rfr_id=info:sid/en.wikipedia.org:HIE-124" class="Z3988">

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Identifiers

IUPAC name Ethyl 8-oxo-6,7-dihydro-5H-[1,3]thiazolo[3,2-a][1,3]diazepine-3-carboxylate
CAS Number	805326-00-5
PubChem CID	11447815
ChemSpider	9622668
UNII	JS6A6EQZ44
ChEMBL	ChEMBL450014
Chemical and physical data
Formula	C₁₀H₁₂N₂O₃S
Molar mass	240.28 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(C1=CSC(N1CCC2)=NC2=O)OCC
InChI InChI=1S/C10H12N2O3S/c1-2-15-9(14)7-6-16-10-11-8(13)4-3-5-12(7)10/h6H,2-5H2,1H3 Key:UXGPDPNGDCOQBY-UHFFFAOYSA-N