In enzymology, a glycosaminoglycan galactosyltransferase (EC 2.4.1.74) is an enzyme that catalyzes the chemical reaction
| glycosaminoglycan galactosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.74 | ||||||||
| CAS no. | 51004-28-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- UDP-galactose glycosaminoglycan UDP D-galactosylglycosaminoglycan
Thus, the two substrates of this enzyme are UDP-galactose and glycosaminoglycan, whereas its two products are UDP and D-galactosylglycosaminoglycan.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:glycosaminoglycan D-galactosyltransferase. This enzyme is also called uridine diphosphogalactose-mucopolysaccharide galactosyltransferase.
References
edit- Sussman M, Osborn MJ (1964). "UDP-glucose polysaccharide transferase in the cellular slime mold Dictyostelium discoideum: appearance and disappearance of activity during cell differentiation". Proc. Natl. Acad. Sci. USA. 52 (1): 81–87. Bibcode:1964PNAS...52...81S. doi:10.1073/pnas.52.1.81. PMC 300577. PMID 14192661.81-87&rft.date=1964&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300577#id-name=PMC&rft_id=info:pmid/14192661&rft_id=info:doi/10.1073/pnas.52.1.81&rft_id=info:bibcode/1964PNAS...52...81S&rft.aulast=Sussman&rft.aufirst=M&rft.au=Osborn, MJ&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300577&rfr_id=info:sid/en.wikipedia.org:Glycosaminoglycan galactosyltransferase" class="Z3988">
