In enzymology, a glucose 1-dehydrogenase (NADP ) (EC 1.1.1.119) is an enzyme that catalyzes the chemical reaction
| glucose 1-dehydrogenase (NADP ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.119 | ||||||||
| CAS no. | 37250-50-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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- D-glucose NADP D-glucono-1,5-lactone NADPH H
Thus, the two substrates of this enzyme are D-glucose and NADP , whereas its 3 products are D-glucono-1,5-lactone, NADPH, and H .
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is D-glucose:NADP 1-oxidoreductase. Other names in common use include nicotinamide adenine dinucleotide phosphate-linked aldohexose, dehydrogenase, NADP -linked aldohexose dehydrogenase, NADP -dependent glucose dehydrogenase, and glucose 1-dehydrogenase (NADP ).
References
edit- Adachi O; Ameyama M (1982). "D-Glucose dehydrogenase from Gluconobacter su☐ydans". Carbohydrate Metabolism - Part D. Methods in Enzymology. Vol. 89. pp. 159–163. doi:10.1016/S0076-6879(82)89028-9. ISBN 978-0-12-181989-7.159-163&rft.date=1982&rft_id=info:doi/10.1016/S0076-6879(82)89028-9&rft.isbn=978-0-12-181989-7&rft.au=Adachi O&rft.au=Ameyama M&rfr_id=info:sid/en.wikipedia.org:Glucose 1-dehydrogenase (NADP+)" class="Z3988">
- Avigad G, Alroy Y, Englard S (1968). "Purification and properties of a nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogeanse from Gluconobacter cerinus". J. Biol. Chem. 243 (8): 1936–41. doi:10.1016/S0021-9258(18)93531-3. PMID 4384672.1936-41&rft.date=1968&rft_id=info:doi/10.1016/S0021-9258(18)93531-3&rft_id=info:pmid/4384672&rft.aulast=Avigad&rft.aufirst=G&rft.au=Alroy, Y&rft.au=Englard, S&rft_id=https://doi.org/10.1016%2FS0021-9258%2818%2993531-3&rfr_id=info:sid/en.wikipedia.org:Glucose 1-dehydrogenase (NADP+)" class="Z3988">
