Folipastatin is a depsidone phospholipase A2 inhibitor which is produced by the fungi Aspergillus unguis and Wicklowia aquatica.[2][3][1] Folipastatin has the molecular formula C23H24O5.[1]
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IUPAC name
1,7-bis[(Z)-but-2-en-2-yl]-3,9-dihydroxy-4,10-dimethylbenzo[b][1,4]benzodioxepin-6-one[1]
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Other names
E323392EAO
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
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Properties | |
C23H24O5 | |
Molar mass | 380.440 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ a b c "Folipastatin". Pubchem.ncbi.NLM.nih.gov.
- ^ Hamano, Kiyoshi; Kinoshita-Okami, Masako; Hemmi, Atsuko; Sato, Akira; Hisamoto, Marie; Matsuda, Keiichi; Yoda, Keiko; Haruyama, Hideyuki; Hosoya, Tsuyoshi; Tanzawa, Kazuhiko (1992). "Folipastatin, a new depsidone compound from Aspergillus unguis as an inhibitor of phospholipase A2. Taxonomy, fermentation, isolation, structure determination and biological properties". The Journal of Antibiotics. 45 (8): 1195–1201. doi:10.7164/antibiotics.45.1195. PMID 1399838.
- ^ Bycroft, Barrie W.; Payne, David J. (9 August 2013). Dictionary of Antibiotics and Related Substances: with CD-ROM, Second Edition. CRC Press. p. 829. ISBN 978-1-4822-8215-3.