Eosin Y

Eosin Y
Names
	IUPAC name 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate [in its deprotonated form]
Identifiers
CAS Number	17372-87-1 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:52053 ;
ChEMBL	ChEMBL411675 ;
ChemSpider	10580 ;
ECHA InfoCard	100.037.629
MeSH	Eosine Yellowish-(YS)
PubChem CID	11048;
UNII	TDQ283MPCW ;
CompTox Dashboard (EPA)	DTXSID901015574 DTXSID0025234, DTXSID901015574 ;
	InChI InChI=1S/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2* 1/p-2 Key: SEACYXSIPDVVMV-UHFFFAOYSA-L ; InChI=1/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2* 1/p-2 Key: SEACYXSIPDVVMV-NUQVWONBAJ;
	SMILES c1ccc(c(c1)c2c3cc(c(c(c3oc-4c(c(=O)c(cc24)Br)Br)Br)[O-])Br)C(=O)[O-].[Na ].[Na ];
Properties
Chemical formula	C20H6Br4Na2O5
Molar mass	647.89052
Appearance	Red powder
Density	1.018 g·cm−3
Melting point	295.5 °C (563.9 °F; 568.6 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Eosin Y, also called C.I. 45380^[1]^[2] or C.I. Acid Red 87,^[2]^[1] is a member of the triarylmethane dyes. It is produced from fluorescein by bromination.^[3]

Use

Eosin Y is commonly used as the red dye in red inks.

It is commonly used in histology, most notably in the H&E (Haematoxylin and Eosin) stain.^[1] Eosin Y is also widely used in the Papanicolaou stain (or Pap stain used in the Pap test) and the Romanowsky type cytologic stains.^[1]^[2] It is also used as a photosensitizer in organic synthesis.^[4]

Eosin Y solution for staining microscopy slides.
Eosinophilic staining, using eosin Y, compared to other patterns when using hematoxylin and eosin (H&E).

References

^ ^a ^b ^c ^d Bancroft, John; Stevens, Alan, eds. (1982). The Theory and Practice of Histological Techniques (2nd ed.). Longman Group Limited.
^ ^a ^b ^c Lillie, Ralph Dougall (1977). H. J. Conn's Biological stains (9th ed.). Baltimore: Williams & Wilkins. pp. 692p.
^ Gessner, Thomas; Mayer, Udo (2000). "Triarylmethane and Diarylmethane Dyes". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a27_179. ISBN 978-3527306732.
^ Diercxsens, Nicolas (2017-04-10), "Eosin Y", Encyclopedia of Reagents for Organic Synthesis, Chichester, UK: John Wiley & Sons, Ltd, pp. 1–3, doi:10.1002/047084289x.rn02033, ISBN 978-0-470-84289-81-3&rft.pub=John Wiley & Sons, Ltd&rft.date=2017-04-10&rft_id=info:doi/10.1002/047084289x.rn02033&rft.isbn=978-0-470-84289-8&rft.aulast=Diercxsens&rft.aufirst=Nicolas&rfr_id=info:sid/en.wikipedia.org:Eosin Y" class="Z3988">

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[Bancroft_and_Stevens,_1982-1] Bancroft, John; Stevens, Alan, eds. (1982). The Theory and Practice of Histological Techniques (2nd ed.). Longman Group Limited.

[Lillie,_1977-2] Lillie, Ralph Dougall (1977). H. J. Conn's Biological stains (9th ed.). Baltimore: Williams & Wilkins. pp. 692p.

[Ull-3] Gessner, Thomas; Mayer, Udo (2000). "Triarylmethane and Diarylmethane Dyes". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a27_179. ISBN 978-3527306732.

[4] Diercxsens, Nicolas (2017-04-10), "Eosin Y", Encyclopedia of Reagents for Organic Synthesis, Chichester, UK: John Wiley & Sons, Ltd, pp. 1–3, doi:10.1002/047084289x.rn02033, ISBN 978-0-470-84289-81-3&rft.pub=John Wiley & Sons, Ltd&rft.date=2017-04-10&rft_id=info:doi/10.1002/047084289x.rn02033&rft.isbn=978-0-470-84289-8&rft.aulast=Diercxsens&rft.aufirst=Nicolas&rfr_id=info:sid/en.wikipedia.org:Eosin Y" class="Z3988">

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Eosin Y

Use

See also

References