The enzyme ectoine synthase (EC [1]) catalyzes the chemical reaction
| Ectoine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.108 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2S)-4-acetamido-2-aminobutanoate L-ectoine H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (2S)-4-acetamido-2-aminobutanoate (L-ectoine-forming). Other names in common use include N-acetyldiaminobutyrate dehydratase, N-acetyldiaminobutanoate dehydratase, L-ectoine synthase, EctC, and 4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming). This enzyme participates in glycine, serine and threonine metabolism.
References
edit- Peters P, Galinski EA, Truper HG (1990). "The biosynthesis of ectoine". FEMS Microbiol. Lett. 71 (1–2): 157–162. doi:10.1111/j.1574-6968.1990.tb03815.x.1–2&rft.pages=157-162&rft.date=1990&rft_id=info:doi/10.1111/j.1574-6968.1990.tb03815.x&rft.aulast=Peters&rft.aufirst=P&rft.au=Galinski, EA&rft.au=Truper, HG&rft_id=https://doi.org/10.1111%2Fj.1574-6968.1990.tb03815.x&rfr_id=info:sid/en.wikipedia.org:Ectoine synthase" class="Z3988">
- Ono H, Sawada K, Khunajakr N, et al. (1999). "Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata". J. Bacteriol. 181 (1): 91–9. PMC 103536. PMID 9864317.91-9&rft.date=1999&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC103536#id-name=PMC&rft_id=info:pmid/9864317&rft.aulast=Ono&rft.aufirst=H&rft.au=Sawada, K&rft.au=Khunajakr, N&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC103536&rfr_id=info:sid/en.wikipedia.org:Ectoine synthase" class="Z3988">
- Kuhlmann AU, Bremer E (2002). "Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp". Appl. Environ. Microbiol. 68 (2): 772–83. doi:10.1128/AEM.68.2.772-783.2002. PMC 126723. PMID 11823218.772-83&rft.date=2002&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126723#id-name=PMC&rft_id=info:pmid/11823218&rft_id=info:doi/10.1128/AEM.68.2.772-783.2002&rft.aulast=Kuhlmann&rft.aufirst=AU&rft.au=Bremer, E&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126723&rfr_id=info:sid/en.wikipedia.org:Ectoine synthase" class="Z3988">
- Louis P, Galinski EA (1997). "Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli". Microbiology. 143 (4): 1141–9. doi:10.1099/00221287-143-4-1141. PMID 9141677.1141-9&rft.date=1997&rft_id=info:doi/10.1099/00221287-143-4-1141&rft_id=info:pmid/9141677&rft.aulast=Louis&rft.aufirst=P&rft.au=Galinski, EA&rft_id=https://doi.org/10.1099%2F00221287-143-4-1141&rfr_id=info:sid/en.wikipedia.org:Ectoine synthase" class="Z3988">
