EXPH5

EXPH5
Identifiers
Aliases	EXPH5, SLAC2-B, SLAC2B, exophilin 5, EBS4
External IDs	OMIM: 612878; MGI: 2443248; HomoloGene: 9007; GeneCards: EXPH5; OMA:EXPH5 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	108,593,768 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	53,288,814 bp
RNA expression pattern
	Top expressed in
	skin of hip; ; mucosa of paranasal sinus; ; amniotic fluid; ; oral cavity; ; skin of thigh; ; bronchial epithelial cell; ; skin of arm; ; nipple; ; nasal epithelium; ; gums;
	Top expressed in
	cerebellar cortex; ; jejunum; ; zone of skin; ; liver; ; ileum; ; esophagus; ; lip; ; stomach; ; spermatocyte; ; lung;
	More reference expression data
	More reference expression data
Orthologs
	23086
	320051
	ENSG00000110723
	ENSMUSG00000034584
	Q8NEV8
	Q0VAV2
	NM_001144763; NM_001144764; NM_001144765; NM_001308019; NM_015065
	NM_176846
	NP_001138235; NP_001138236; NP_001138237; NP_001294948; NP_055880
	NP_789816
	Wikidata
View/Edit Human	View/Edit Mouse

Exophilin 5, also known as EXPH5, is a human gene.^[5]

Interactions

EXPH5 has been shown to interact with RAB27A.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110723 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034584 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: EXPH5 exophilin 5".
^ Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (Mar 2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.9212-8&rft.date=2002-03&rft_id=info:doi/10.1074/jbc.M112414200&rft_id=info:pmid/11773082&rft.aulast=Kuroda&rft.aufirst=TS&rft.au=Fukuda, M&rft.au=Ariga, H&rft.au=Mikoshiba, K&rft_id=https://doi.org/10.1074%2Fjbc.M112414200&rfr_id=info:sid/en.wikipedia.org:EXPH5" class="Z3988">

Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.1324-32&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442148#id-name=PMC&rft_id=info:pmid/15231748&rft_id=info:doi/10.1101/gr.2334104&rft.aulast=Colland&rft.aufirst=F&rft.au=Jacq, X&rft.au=Trouplin, V&rft.au=Mougin, C&rft.au=Groizeleau, C&rft.au=Hamburger, A&rft.au=Meil, A&rft.au=Wojcik, J&rft.au=Legrain, P&rft.au=Gauthier, JM&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442148&rfr_id=info:sid/en.wikipedia.org:EXPH5" class="Z3988">
Fukuda M (2003). "Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells". J. Biol. Chem. 278 (17): 15390–6. doi:10.1074/jbc.M213090200. PMID 12590134.15390-6&rft.date=2003&rft_id=info:doi/10.1074/jbc.M213090200&rft_id=info:pmid/12590134&rft.aulast=Fukuda&rft.aufirst=M&rft_id=https://doi.org/10.1074%2Fjbc.M213090200&rfr_id=info:sid/en.wikipedia.org:EXPH5" class="Z3988">
Fukuda M (2002). "Synaptotagmin-like protein (Slp) homology domain 1 of Slac2-a/melanophilin is a critical determinant of GTP-dependent specific binding to Rab27A". J. Biol. Chem. 277 (42): 40118–24. doi:10.1074/jbc.M205765200. PMID 12189142.40118-24&rft.date=2002&rft_id=info:doi/10.1074/jbc.M205765200&rft_id=info:pmid/12189142&rft.aulast=Fukuda&rft.aufirst=M&rft_id=https://doi.org/10.1074%2Fjbc.M205765200&rfr_id=info:sid/en.wikipedia.org:EXPH5" class="Z3988">
Nagashima K, Torii S, Yi Z, Igarashi M, Okamoto K, Takeuchi T, Izumi T (2002). "Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions". FEBS Lett. 517 (1–3): 233–8. Bibcode:2002FEBSL.517..233N. doi:10.1016/S0014-5793(02)02634-0. PMID 12062444. S2CID 14844547.1–3&rft.pages=233-8&rft.date=2002&rft_id=info:doi/10.1016/S0014-5793(02)02634-0&rft_id=https://api.semanticscholar.org/CorpusID:14844547#id-name=S2CID&rft_id=info:pmid/12062444&rft_id=info:bibcode/2002FEBSL.517..233N&rft.aulast=Nagashima&rft.aufirst=K&rft.au=Torii, S&rft.au=Yi, Z&rft.au=Igarashi, M&rft.au=Okamoto, K&rft.au=Takeuchi, T&rft.au=Izumi, T&rft_id=https://doi.org/10.1016%2FS0014-5793%2802%2902634-0&rfr_id=info:sid/en.wikipedia.org:EXPH5" class="Z3988">
Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.9212-8&rft.date=2002&rft_id=info:doi/10.1074/jbc.M112414200&rft_id=info:pmid/11773082&rft.aulast=Kuroda&rft.aufirst=TS&rft.au=Fukuda, M&rft.au=Ariga, H&rft.au=Mikoshiba, K&rft_id=https://doi.org/10.1074%2Fjbc.M112414200&rfr_id=info:sid/en.wikipedia.org:EXPH5" class="Z3988">
Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.169-76&rft.date=1998&rft_id=info:doi/10.1093/dnares/5.3.169&rft_id=info:pmid/9734811&rft.aulast=Ishikawa&rft.aufirst=K&rft.au=Nagase, T&rft.au=Suyama, M&rft.au=Miyajima, N&rft.au=Tanaka, A&rft.au=Kotani, H&rft.au=Nomura, N&rft.au=Ohara, O&rft_id=https://doi.org/10.1093%2Fdnares%2F5.3.169&rfr_id=info:sid/en.wikipedia.org:EXPH5" class="Z3988">

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000110723 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034584 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: EXPH5 exophilin 5".

[pmid11773082-6] Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (Mar 2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.9212-8&rft.date=2002-03&rft_id=info:doi/10.1074/jbc.M112414200&rft_id=info:pmid/11773082&rft.aulast=Kuroda&rft.aufirst=TS&rft.au=Fukuda, M&rft.au=Ariga, H&rft.au=Mikoshiba, K&rft_id=https://doi.org/10.1074%2Fjbc.M112414200&rfr_id=info:sid/en.wikipedia.org:EXPH5" class="Z3988">

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EXPH5

Interactions

References

Further reading