 | Draft article not currently submitted for review.
This is a draft Articles for creation (AfC) submission. It is not currently pending review. While there are no deadlines, abandoned drafts may be deleted after six months. To edit the draft click on the "Edit" tab at the top of the window. To be accepted, a draft should:
It is strongly discouraged to write about yourself, your business or employer. If you do so, you must declare it. Where to get help
How to improve a draft
You can also browse Wikipedia:Featured articles and Wikipedia:Good articles to find examples of Wikipedia's best writing on topics similar to your proposed article. Improving your odds of a speedy review To improve your odds of a faster review, tag your draft with relevant WikiProject tags using the button below. This will let reviewers know a new draft has been submitted in their area of interest. For instance, if you wrote about a female astronomer, you would want to add the Biography, Astronomy, and Women scientists tags. Editor resources
Last edited by Cjhallinan (talk | contribs) 0 seconds ago. (Update) |
Mikala Egeblad is an internationally renowned cancer researcher who is a professor of Oncology and Cell Biology at Johns Hopkins School of Medicine.
Education
editEgeblad attended the University of Copenhagen where she earned a bachelor’s degree in medicine, a master’s degree in human biology and a PhD in cancer biology. Following her PhD, she trained as a postdoctoral fellow in Zena Werb’s laboratory at University of California, San Francisco. While there, she used mouse models to research the cancerous tumor microenvironment, focusing on the contribution of the innate immune system and matrix metalloproteinases. Egeblad also co-developed a technique of intravital imaging, using a 2-photon microscope and silicone window implant to capture immune cell behavior in real time.
Career
editIn 2009, she established her own lab at Cold Spring Harbor Laboratory in New York where she continued to study the tumor microenvironment, publishing influential findings on the interactions between cancer cells and their surrounding stromal cells. Her work has helped define the mechanisms by which neutrophils induce the progression of cancer and its metastasis.
In 2023, Egeblad joined Johns Hopkins School of Medicine as a Bloomberg Distinguished Professor, where she has been appointed as a professor in both the Department of Cell Biology and the Department of Oncology. Egeblad is also a member of the Convergence Institute, a co-director of the Cancer Invasion Metastasis Program in the Sidney Kimmel Comprehensive Cancer Center and an associate director of the Giovanis Institute for Translational Cell Biology at Hopkins.
Research
editMikala Egeblad’s work focuses on understanding how the body’s immune response influences cancer progression, metastasis, and therapy outcomes. Her lab’s research centers on the tumor microenvironment—the immune cells, blood vessels, stroma and signaling pathways surrounding a tumor—and how this environment shapes cancer growth and spread. Her lab has made groundbreaking discoveries regarding the role of neutrophils and their extracellular traps (NETs) in the advancement of cancer. Additionally, the Egeblad lab has identified a crucial link between stress, immune response and cancer metastasis.
With the standing goal of preventing metastasis and finding more effective ways to fight cancer, Egeblad and her lab continue to drive projects across a variety of cancer models, using cutting-edge imaging techniques and innovative approaches.