Dimetotiazine

Dimetotiazine
Clinical data
Other names	Dimethothiazine
AHFS/Drugs.com	International Drug Names
Routes of; administration	By mouth
ATC code	N02CX05 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 10-(2-Dimethylaminopropyl)-N,N-dimethylphenothiazine-2-sulfonamide;
CAS Number	7456-24-8 ;
PubChem CID	3089;
DrugBank	DB08967 ;
ChemSpider	2979 ;
UNII	1FTA475ZDB;
KEGG	D07854 ;
CompTox Dashboard (EPA)	DTXSID6023076 ;
ECHA InfoCard	100.028.390
Chemical and physical data
Formula	C19H25N3O2S2
Molar mass	391.55 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)S(=O)(=O)N(C)C)N(C)C;
	InChI InChI=1S/C19H25N3O2S2/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5/h6-12,14H,13H2,1-5H3 ; Key:VWNWVCJGUMZDIU-UHFFFAOYSA-N ;
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Dimetotiazine (INN) is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist.^[1]

References

^ Shimazawa M, Hara H, Watano T, Sukamoto T (August 1995). "Effects of Ca2 channel blockers on cortical hypoperfusion and expression of c-Fos-like immunoreactivity after cortical spreading depression in rats". British Journal of Pharmacology. 115 (8): 1359–68. doi:10.1111/j.1476-5381.1995.tb16624.x. PMC 1908864. PMID 8564192.1359-68&rft.date=1995-08&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1908864#id-name=PMC&rft_id=info:pmid/8564192&rft_id=info:doi/10.1111/j.1476-5381.1995.tb16624.x&rft.aulast=Shimazawa&rft.aufirst=M&rft.au=Hara, H&rft.au=Watano, T&rft.au=Sukamoto, T&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1908864&rfr_id=info:sid/en.wikipedia.org:Dimetotiazine" class="Z3988">

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