In enzymology, a dihydrobunolol dehydrogenase (EC 1.1.1.160) is an enzyme that catalyzes the chemical reaction
| dihydrobunolol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.160 | ||||||||
| CAS no. | 62213-61-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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- ( /−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1- naphthol NADP ( /−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)- naphthalenone NADPH H
The three substrates of this enzyme are [[( /−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol]], and NADP , whereas its 4 products are [[( /−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-]], naphthalenone, NADPH, and H .
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is ( /−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP oxidoreductase. This enzyme is also termed bunolol reductase.
References
edit- Leinweber FJ, Greenough RC, Schwender CF, Kaplan HR, Di Carlo FJ (1972). "Bunolol metabolism by cell-free preparations of human liver: biosynthesis of dihydrobunolol". Xenobiotica. 2 (2): 191–202. doi:10.3109/00498257209111050. PMID 4560367.191-202&rft.date=1972&rft_id=info:doi/10.3109/00498257209111050&rft_id=info:pmid/4560367&rft.aulast=Leinweber&rft.aufirst=FJ&rft.au=Greenough, RC&rft.au=Schwender, CF&rft.au=Kaplan, HR&rft.au=Di Carlo, FJ&rfr_id=info:sid/en.wikipedia.org:Dihydrobunolol dehydrogenase" class="Z3988">
- Leinweber FJ, Greenough RC, Schwender CF, Kaplan HR, Di Carlo FJ (1972). "Bunolol metabolism by cell-free preparations of human liver: biosynthesis of dihydrobunolol". Xenobiotica. 2 (2): 191–202. doi:10.3109/00498257209111050. PMID 4560367.191-202&rft.date=1972&rft_id=info:doi/10.3109/00498257209111050&rft_id=info:pmid/4560367&rft.aulast=Leinweber&rft.aufirst=FJ&rft.au=Greenough, RC&rft.au=Schwender, CF&rft.au=Kaplan, HR&rft.au=Di Carlo, FJ&rfr_id=info:sid/en.wikipedia.org:Dihydrobunolol dehydrogenase" class="Z3988">
