DNAJC14

DNAJC14
Identifiers
Aliases	DNAJC14, DNAJ, DRIP78, HDJ3, LIP6, DnaJ heat shock protein family (Hsp40) member C14
External IDs	OMIM: 606092; MGI: 1921580; HomoloGene: 12553; GeneCards: DNAJC14; OMA:DNAJC14 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	55,830,824 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	128,655,315 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; mucosa of ileum; ; stromal cell of endometrium; ; granulocyte; ; smooth muscle tissue; ; monocyte; ; tibialis anterior muscle; ; appendix; ; rectum; ; prefrontal cortex;
	Top expressed in
	lacrimal gland; ; primary oocyte; ; secondary oocyte; ; granulocyte; ; right lung lobe; ; external carotid artery; ; internal carotid artery; ; lip; ; zygote; ; tail of embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor binding; dopamine receptor binding;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; extracellular exosome; endoplasmic reticulum;
Biological process	protein transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	85406
	74330
	ENSG00000135392
	ENSMUSG00000025354
	Q6Y2X3
	Q921R4
	NM_032364
	NM_028873; NM_001359824; NM_001359825
	NP_115740
	NP_083149; NP_001346753; NP_001346754
	Wikidata
View/Edit Human	View/Edit Mouse

DnaJ homolog subfamily C member 14 is a protein that in humans is encoded by the DNAJC14 gene.^[5]^[6]^[7]

Interactions

DNAJC14 has been shown to interact with Dopamine receptor D1.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135392 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025354 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Bermak JC, Li M, Bullock C, Zhou QY (May 2001). "Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein". Nat Cell Biol. 3 (5): 492–8. doi:10.1038/35074561. PMID 11331877. S2CID 40809366.492-8&rft.date=2001-05&rft_id=https://api.semanticscholar.org/CorpusID:40809366#id-name=S2CID&rft_id=info:pmid/11331877&rft_id=info:doi/10.1038/35074561&rft.aulast=Bermak&rft.aufirst=JC&rft.au=Li, M&rft.au=Bullock, C&rft.au=Zhou, QY&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">
^ Tchernev VT, Mansfield TA, Giot L, Kumar AM, Nandabalan K, Li Y, Mishra VS, Detter JC, Rothberg JM, Wallace MR, Southwick FS, Kingsmore SF (May 2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Mol Med. 8 (1): 56–64. doi:10.1007/bf03402003. PMC 2039936. PMID 11984006.56-64&rft.date=2002-05&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039936#id-name=PMC&rft_id=info:pmid/11984006&rft_id=info:doi/10.1007/bf03402003&rft.aulast=Tchernev&rft.aufirst=VT&rft.au=Mansfield, TA&rft.au=Giot, L&rft.au=Kumar, AM&rft.au=Nandabalan, K&rft.au=Li, Y&rft.au=Mishra, VS&rft.au=Detter, JC&rft.au=Rothberg, JM&rft.au=Wallace, MR&rft.au=Southwick, FS&rft.au=Kingsmore, SF&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039936&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">
^ "Entrez Gene: DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14".

Bermak JC, Zhou QY (2004). "Accessory proteins in the biogenesis of G protein-coupled receptors". Mol. Interv. 1 (5): 282–7. PMID 14993367.282-7&rft.date=2004&rft_id=info:pmid/14993367&rft.aulast=Bermak&rft.aufirst=JC&rft.au=Zhou, QY&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">
Leclerc PC, Auger-Messier M, Lanctot PM, et al. (2002). "A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin II plays an important role in receptor trafficking and signaling". Endocrinology. 143 (12): 4702–10. doi:10.1210/en.2002-220679. PMID 12446598.4702-10&rft.date=2002&rft_id=info:doi/10.1210/en.2002-220679&rft_id=info:pmid/12446598&rft.aulast=Leclerc&rft.aufirst=PC&rft.au=Auger-Messier, M&rft.au=Lanctot, PM&rft_id=https://doi.org/10.1210%2Fen.2002-220679&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.16899-903&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241#id-name=PMC&rft_id=info:pmid/12477932&rft_id=info:doi/10.1073/pnas.242603899&rft_id=info:bibcode/2002PNAS...9916899M&rft.aulast=Strausberg&rft.aufirst=RL&rft.au=Feingold, EA&rft.au=Grouse, LH&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">
Chen J, Huang Y, Wu H, et al. (2003). "Molecular cloning and characterization of a novel human J-domain protein gene (HDJ3) from the fetal brain". J. Hum. Genet. 48 (5): 217–21. doi:10.1007/s10038-003-0012-8. PMID 12768437.217-21&rft.date=2003&rft_id=info:doi/10.1007/s10038-003-0012-8&rft_id=info:pmid/12768437&rft.aulast=Chen&rft.aufirst=J&rft.au=Huang, Y&rft.au=Wu, H&rft_id=https://doi.org/10.1007%2Fs10038-003-0012-8&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.40-5&rft.date=2004&rft_id=info:doi/10.1038/ng1285&rft_id=info:pmid/14702039&rft.aulast=Ota&rft.aufirst=T&rft.au=Suzuki, Y&rft.au=Nishikawa, T&rft_id=https://doi.org/10.1038%2Fng1285&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.2121-7&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928#id-name=PMC&rft_id=info:pmid/15489334&rft_id=info:doi/10.1101/gr.2596504&rft.aulast=Gerhard&rft.aufirst=DS&rft.au=Wagner, L&rft.au=Feingold, EA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.55-65&rft.date=2006&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129#id-name=PMC&rft_id=info:pmid/16344560&rft_id=info:doi/10.1101/gr.4039406&rft.aulast=Kimura&rft.aufirst=K&rft.au=Wakamatsu, A&rft.au=Suzuki, Y&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135392 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025354 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11331877-5] Bermak JC, Li M, Bullock C, Zhou QY (May 2001). "Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein". Nat Cell Biol. 3 (5): 492–8. doi:10.1038/35074561. PMID 11331877. S2CID 40809366.492-8&rft.date=2001-05&rft_id=https://api.semanticscholar.org/CorpusID:40809366#id-name=S2CID&rft_id=info:pmid/11331877&rft_id=info:doi/10.1038/35074561&rft.aulast=Bermak&rft.aufirst=JC&rft.au=Li, M&rft.au=Bullock, C&rft.au=Zhou, QY&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">

[pmid11984006-6] Tchernev VT, Mansfield TA, Giot L, Kumar AM, Nandabalan K, Li Y, Mishra VS, Detter JC, Rothberg JM, Wallace MR, Southwick FS, Kingsmore SF (May 2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Mol Med. 8 (1): 56–64. doi:10.1007/bf03402003. PMC 2039936. PMID 11984006.56-64&rft.date=2002-05&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039936#id-name=PMC&rft_id=info:pmid/11984006&rft_id=info:doi/10.1007/bf03402003&rft.aulast=Tchernev&rft.aufirst=VT&rft.au=Mansfield, TA&rft.au=Giot, L&rft.au=Kumar, AM&rft.au=Nandabalan, K&rft.au=Li, Y&rft.au=Mishra, VS&rft.au=Detter, JC&rft.au=Rothberg, JM&rft.au=Wallace, MR&rft.au=Southwick, FS&rft.au=Kingsmore, SF&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039936&rfr_id=info:sid/en.wikipedia.org:DNAJC14" class="Z3988">

[entrez-7] "Entrez Gene: DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14".

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DNAJC14

Interactions

References

Further reading