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In enzymology, a D-arabinose 1-dehydrogenase [NAD(P) ] (EC 1.1.1.117) is an enzyme that catalyzes the chemical reaction
| D-arabinose 1-dehydrogenase [NAD(P) ] | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.117 | ||||||||
| CAS no. | 37250-48-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- D-arabinose NAD(P) D-arabinono-1,4-lactone NAD(P)H H
The 3 substrates of this enzyme are D-arabinose, NAD , and NADP , whereas its 4 products are D-arabinono-1,4-lactone, NADH, NADPH, and H .
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is D-arabinose:NAD(P) 1-oxidoreductase. This enzyme is also called D-arabinose 1-dehydrogenase [NAD(P) ].
Structural studies
editAs of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2H6E.
References
edit- Cline AL, Hu AS (1965). "The isolation of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240 (11): 4488–92. doi:10.1016/S0021-9258(18)97087-0. PMID 5845847.4488-92&rft.date=1965&rft_id=info:doi/10.1016/S0021-9258(18)97087-0&rft_id=info:pmid/5845847&rft.aulast=Cline&rft.aufirst=AL&rft.au=Hu, AS&rft_id=https://doi.org/10.1016%2FS0021-9258%2818%2997087-0&rfr_id=info:sid/en.wikipedia.org:D-arabinose 1-dehydrogenase (NAD(P)+)" class="Z3988">
- Cline AL, Hu AS (1965). "Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240 (11): 4493–7. doi:10.1016/S0021-9258(18)97088-2. PMID 5845848.4493-7&rft.date=1965&rft_id=info:doi/10.1016/S0021-9258(18)97088-2&rft_id=info:pmid/5845848&rft.aulast=Cline&rft.aufirst=AL&rft.au=Hu, AS&rft_id=https://doi.org/10.1016%2FS0021-9258%2818%2997088-2&rfr_id=info:sid/en.wikipedia.org:D-arabinose 1-dehydrogenase (NAD(P)+)" class="Z3988">
- Cline AL, Hu AS (1965). "Some physical properties of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240 (11): 4498–502. doi:10.1016/S0021-9258(18)97089-4. PMID 5845849.4498-502&rft.date=1965&rft_id=info:doi/10.1016/S0021-9258(18)97089-4&rft_id=info:pmid/5845849&rft.aulast=Cline&rft.aufirst=AL&rft.au=Hu, AS&rft_id=https://doi.org/10.1016%2FS0021-9258%2818%2997089-4&rfr_id=info:sid/en.wikipedia.org:D-arabinose 1-dehydrogenase (NAD(P)+)" class="Z3988">
