In enzymology, a cyclohexanol dehydrogenase (EC 1.1.1.245) is an enzyme that catalyzes the chemical reaction
| cyclohexanol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.245 | ||||||||
| CAS no. | 63951-98-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- cyclohexanol NAD cyclohexanone NADH H
Thus, the two substrates of this enzyme are cyclohexanol and NAD , whereas its 3 products are cyclohexanone, NADH, and H .
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is cyclohexanol:NAD oxidoreductase. This enzyme participates in caprolactam degradation.
References
edit- Dangel W, Tschech A, Fuchs G (1989). "Enzyme-reactions involved in anaerobic cyclohexanol metabolism by a denitrifying Pseudomonas species". Arch. Microbiol. 152 (3): 273–279. doi:10.1007/BF00409663. PMID 2505723.273-279&rft.date=1989&rft_id=info:doi/10.1007/BF00409663&rft_id=info:pmid/2505723&rft.aulast=Dangel&rft.aufirst=W&rft.au=Tschech, A&rft.au=Fuchs, G&rfr_id=info:sid/en.wikipedia.org:Cyclohexanol dehydrogenase" class="Z3988">
- Donoghue NA, Trudgill PW (1975). "The metabolism of cyclohexanol by Acinetobacter NCIB 9871". Eur. J. Biochem. 60 (1): 1–7. doi:10.1111/j.1432-1033.1975.tb20968.x. PMID 1261.1-7&rft.date=1975&rft_id=info:doi/10.1111/j.1432-1033.1975.tb20968.x&rft_id=info:pmid/1261&rft.aulast=Donoghue&rft.aufirst=NA&rft.au=Trudgill, PW&rft_id=https://doi.org/10.1111%2Fj.1432-1033.1975.tb20968.x&rfr_id=info:sid/en.wikipedia.org:Cyclohexanol dehydrogenase" class="Z3988">
- Trower MK, Buckland RM, Higgins R, Griffin M (1985). "Isolation and Characterization of a Cyclohexane-Metabolizing Xanthobacter sp". Appl. Environ. Microbiol. 49 (5): 1282–1289. PMC 238543. PMID 16346796.1282-1289&rft.date=1985&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC238543#id-name=PMC&rft_id=info:pmid/16346796&rft.aulast=Trower&rft.aufirst=MK&rft.au=Buckland, RM&rft.au=Higgins, R&rft.au=Griffin, M&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC238543&rfr_id=info:sid/en.wikipedia.org:Cyclohexanol dehydrogenase" class="Z3988">
