cis-Abienol synthase (EC 4.2.3.140, Z-abienol synthase, CAS, ABS) is an enzyme with systematic name (13E)-8α-hydroxylabd-13-en-15-yl-diphosphate-lyase (cis-abienol forming).[1][2] This enzyme catalyses the following chemical reaction
| cis-abienol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.140 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (13E)-8α-hydroxylabd-13-en-15-yl diphosphate cis-abienol diphosphate
This enzyme is isolated from the plants Abies balsamea (balsam fir) and Nicotiana tabacum (tobacco).
References
edit- ^ Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J (April 2012). "Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production". The Journal of Biological Chemistry. 287 (15): 12121–31. doi:10.1074/jbc.m111.317669. PMC 3320957. PMID 22337889.12121-31&rft.date=2012-04&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320957#id-name=PMC&rft_id=info:pmid/22337889&rft_id=info:doi/10.1074/jbc.m111.317669&rft.aulast=Zerbe&rft.aufirst=P&rft.au=Chiang, A&rft.au=Yuen, M&rft.au=Hamberger, B&rft.au=Hamberger, B&rft.au=Draper, JA&rft.au=Britton, R&rft.au=Bohlmann, J&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320957&rfr_id=info:sid/en.wikipedia.org:Cis-abienol synthase" class="Z3988">
- ^ Sallaud C, Giacalone C, Töpfer R, Goepfert S, Bakaher N, Rösti S, Tissier A (October 2012). "Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes". The Plant Journal. 72 (1): 1–17. doi:10.1111/j.1365-313x.2012.05068.x. PMID 22672125.1-17&rft.date=2012-10&rft_id=info:doi/10.1111/j.1365-313x.2012.05068.x&rft_id=info:pmid/22672125&rft.aulast=Sallaud&rft.aufirst=C&rft.au=Giacalone, C&rft.au=Töpfer, R&rft.au=Goepfert, S&rft.au=Bakaher, N&rft.au=Rösti, S&rft.au=Tissier, A&rft_id=https://doi.org/10.1111%2Fj.1365-313x.2012.05068.x&rfr_id=info:sid/en.wikipedia.org:Cis-abienol synthase" class="Z3988">
External links
edit- Cis-abienol synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
