CSDC2

CSDC2
Identifiers
Aliases	CSDC2, PIPPIN, dJ347H13.2, cold shock domain containing C2
External IDs	OMIM: 617689; MGI: 2146027; HomoloGene: 8701; GeneCards: CSDC2; OMA:CSDC2 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	41,577,741 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	81,835,142 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right auricle; ; left ventricle; ; right coronary artery; ; left adrenal cortex; ; right adrenal gland; ; left ovary; ; right adrenal cortex; ; right ovary; ; popliteal artery;
	Top expressed in
	pontine nuclei; ; medial geniculate nucleus; ; gastrula; ; medial vestibular nucleus; ; medial dorsal nucleus; ; dorsal tegmental nucleus; ; inferior colliculi; ; motor neuron; ; cerebellar cortex; ; cerebellar vermis;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; RNA binding; nucleic acid binding; mRNA 3'-UTR binding; transcription factor binding;
Cellular component	nucleus; cytoplasm;
Biological process	mRNA processing; regulation of transcription, DNA-templated; regulation of mRNA stability;
	Sources:Amigo / QuickGO
Orthologs
	27254
	105859
	ENSG00000172346
	ENSMUSG00000042109
	Q9Y534
	Q91YQ3
	NM_014460
	NM_145473
	NP_055275
	NP_663448
	Wikidata
View/Edit Human	View/Edit Mouse

Cold shock domain-containing protein C2 is a protein that in humans is encoded by the CSDC2 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000172346 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042109 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Castiglia D, Scaturro M, Nastasi T, Cestelli A, Di Liegro I (Mar 1996). "PIPPin, a putative RNA-binding protein specifically expressed in the rat brain". Biochem Biophys Res Commun. 218 (1): 390–4. doi:10.1006/bbrc.1996.0068. PMID 8573167.390-4&rft.date=1996-03&rft_id=info:doi/10.1006/bbrc.1996.0068&rft_id=info:pmid/8573167&rft.aulast=Castiglia&rft.aufirst=D&rft.au=Scaturro, M&rft.au=Nastasi, T&rft.au=Cestelli, A&rft.au=Di Liegro, I&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
^ Raimondi L, D'Asaro M, Proia P, Nastasi T, Di Liegro I (May 2003). "RNA-binding ability of PIPPin requires the entire protein". J Cell Mol Med. 7 (1): 35–42. doi:10.1111/j.1582-4934.2003.tb00200.x. PMC 6740078. PMID 12767259.35-42&rft.date=2003-05&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740078#id-name=PMC&rft_id=info:pmid/12767259&rft_id=info:doi/10.1111/j.1582-4934.2003.tb00200.x&rft.aulast=Raimondi&rft.aufirst=L&rft.au=D'Asaro, M&rft.au=Proia, P&rft.au=Nastasi, T&rft.au=Di Liegro, I&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740078&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
^ "Entrez Gene: CSDC2 cold shock domain containing C2, RNA binding".

External links

Human CSDC2 genome location and CSDC2 gene details page in the UCSC Genome Browser.

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.107-13&rft.date=1996&rft_id=info:doi/10.1006/abio.1996.0138&rft_id=info:pmid/8619474&rft.aulast=Andersson&rft.aufirst=B&rft.au=Wentland, MA&rft.au=Ricafrente, JY&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.353-8&rft.date=1997&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139146#id-name=PMC&rft_id=info:pmid/9110174&rft_id=info:doi/10.1101/gr.7.4.353&rft.aulast=Yu&rft.aufirst=W&rft.au=Andersson, B&rft.au=Worley, KC&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139146&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
Nastasi T, Scaturro M, Bellafiore M, et al. (1999). "PIPPin is a brain-specific protein that contains a cold-shock domain and binds specifically to H1 degrees and H3.3 mRNAs". J. Biol. Chem. 274 (34): 24087–93. doi:10.1074/jbc.274.34.24087. PMID 10446180.24087-93&rft.date=1999&rft_id=info:doi/10.1074/jbc.274.34.24087&rft_id=info:pmid/10446180&rft.aulast=Nastasi&rft.aufirst=T&rft.au=Scaturro, M&rft.au=Bellafiore, M&rft_id=https://doi.org/10.1074%2Fjbc.274.34.24087&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.489-95&rft.date=1999&rft_id=info:pmid/10591208&rft_id=info:doi/10.1038/990031&rft_id=info:bibcode/1999Natur.402..489D&rft.aulast=Dunham&rft.aufirst=I&rft.au=Shimizu, N&rft.au=Roe, BA&rft_id=https://doi.org/10.1038%2F990031&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
Nastasi T, Muzi P, Beccari S, et al. (2001). "Specific neurons of brain cortex and cerebellum are PIPPin positive". NeuroReport. 11 (10): 2233–6. doi:10.1097/00001756-200007140-00034. PMID 10923677. S2CID 28313328.2233-6&rft.date=2001&rft_id=https://api.semanticscholar.org/CorpusID:28313328#id-name=S2CID&rft_id=info:pmid/10923677&rft_id=info:doi/10.1097/00001756-200007140-00034&rft.aulast=Nastasi&rft.aufirst=T&rft.au=Muzi, P&rft.au=Beccari, S&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.16899-903&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241#id-name=PMC&rft_id=info:pmid/12477932&rft_id=info:doi/10.1073/pnas.242603899&rft_id=info:bibcode/2002PNAS...9916899M&rft.aulast=Strausberg&rft.aufirst=RL&rft.au=Feingold, EA&rft.au=Grouse, LH&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
Schäfer C, Steffen H, Krzykowski KJ, et al. (2003). "CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells". Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4): G726–34. doi:10.1152/ajpgi.00111.2003. PMID 12801884.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.2121-7&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928#id-name=PMC&rft_id=info:pmid/15489334&rft_id=info:doi/10.1101/gr.2596504&rft.aulast=Gerhard&rft.aufirst=DS&rft.au=Wagner, L&rft.au=Feingold, EA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.55-65&rft.date=2006&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129#id-name=PMC&rft_id=info:pmid/16344560&rft_id=info:doi/10.1101/gr.4039406&rft.aulast=Kimura&rft.aufirst=K&rft.au=Wakamatsu, A&rft.au=Suzuki, Y&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">

This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000172346 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042109 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8573167-5] Castiglia D, Scaturro M, Nastasi T, Cestelli A, Di Liegro I (Mar 1996). "PIPPin, a putative RNA-binding protein specifically expressed in the rat brain". Biochem Biophys Res Commun. 218 (1): 390–4. doi:10.1006/bbrc.1996.0068. PMID 8573167.390-4&rft.date=1996-03&rft_id=info:doi/10.1006/bbrc.1996.0068&rft_id=info:pmid/8573167&rft.aulast=Castiglia&rft.aufirst=D&rft.au=Scaturro, M&rft.au=Nastasi, T&rft.au=Cestelli, A&rft.au=Di Liegro, I&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">

[pmid12767259-6] Raimondi L, D'Asaro M, Proia P, Nastasi T, Di Liegro I (May 2003). "RNA-binding ability of PIPPin requires the entire protein". J Cell Mol Med. 7 (1): 35–42. doi:10.1111/j.1582-4934.2003.tb00200.x. PMC 6740078. PMID 12767259.35-42&rft.date=2003-05&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740078#id-name=PMC&rft_id=info:pmid/12767259&rft_id=info:doi/10.1111/j.1582-4934.2003.tb00200.x&rft.aulast=Raimondi&rft.aufirst=L&rft.au=D'Asaro, M&rft.au=Proia, P&rft.au=Nastasi, T&rft.au=Di Liegro, I&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740078&rfr_id=info:sid/en.wikipedia.org:CSDC2" class="Z3988">

[entrez-7] "Entrez Gene: CSDC2 cold shock domain containing C2, RNA binding".

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CSDC2

References

External links

Further reading