DNA-directed RNA polymerase I subunit RPA34 is an enzyme that in humans is encoded by the CD3EAP gene.[5][6][7][8]
Interactions
editCD3EAP has been shown to interact with T-cell surface glycoprotein CD3 epsilon chain,[5] POLR1E[7] and POLR1C.[7]
References
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000117877 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047649 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b Yamazaki T, Hamano Y, Tashiro H, Itoh K, Nakano H, Miyatake S, Saito T (Jul 1999). "CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells". J Biol Chem. 274 (26): 18173–80. doi:10.1074/jbc.274.26.18173. PMID 10373416.18173-80&rft.date=1999-07&rft_id=info:doi/10.1074/jbc.274.26.18173&rft_id=info:pmid/10373416&rft.aulast=Yamazaki&rft.aufirst=T&rft.au=Hamano, Y&rft.au=Tashiro, H&rft.au=Itoh, K&rft.au=Nakano, H&rft.au=Miyatake, S&rft.au=Saito, T&rft_id=https://doi.org/10.1074%2Fjbc.274.26.18173&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- ^ Whitehead CM, Winkfein RJ, Fritzler MJ, Rattner JB (Mar 1998). "ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes". Chromosoma. 106 (8): 493–502. doi:10.1007/s004120050271. PMID 9426281. S2CID 10684078.493-502&rft.date=1998-03&rft_id=https://api.semanticscholar.org/CorpusID:10684078#id-name=S2CID&rft_id=info:pmid/9426281&rft_id=info:doi/10.1007/s004120050271&rft.aulast=Whitehead&rft.aufirst=CM&rft.au=Winkfein, RJ&rft.au=Fritzler, MJ&rft.au=Rattner, JB&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- ^ a b c Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T, Muramatsu M (Jun 2004). "Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription". Mol Cell Biol. 24 (14): 6338–49. doi:10.1128/MCB.24.14.6338-6349.2004. PMC 434256. PMID 15226435.6338-49&rft.date=2004-06&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC434256#id-name=PMC&rft_id=info:pmid/15226435&rft_id=info:doi/10.1128/MCB.24.14.6338-6349.2004&rft.aulast=Yamamoto&rft.aufirst=K&rft.au=Yamamoto, M&rft.au=Hanada, K&rft.au=Nogi, Y&rft.au=Matsuyama, T&rft.au=Muramatsu, M&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC434256&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- ^ "Entrez Gene: CD3EAP CD3e molecule, epsilon associated protein".
Further reading
edit- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.16899-903&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241#id-name=PMC&rft_id=info:pmid/12477932&rft_id=info:doi/10.1073/pnas.242603899&rft_id=info:bibcode/2002PNAS...9916899M&rft.aulast=Strausberg&rft.aufirst=RL&rft.au=Feingold, EA&rft.au=Grouse, LH&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.97-105&rft.date=2004&rft_id=https://api.semanticscholar.org/CorpusID:11683986#id-name=S2CID&rft_id=info:pmid/14743216&rft_id=info:doi/10.1038/ncb1086&rft.aulast=Bouwmeester&rft.aufirst=T&rft.au=Bauch, A&rft.au=Ruffner, H&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.12130-5&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514446#id-name=PMC&rft_id=info:pmid/15302935&rft_id=info:doi/10.1073/pnas.0404720101&rft_id=info:bibcode/2004PNAS..10112130B&rft.aulast=Beausoleil&rft.aufirst=SA&rft.au=Jedrychowski, M&rft.au=Schwartz, D&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514446&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.2121-7&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928#id-name=PMC&rft_id=info:pmid/15489334&rft_id=info:doi/10.1101/gr.2596504&rft.aulast=Gerhard&rft.aufirst=DS&rft.au=Wagner, L&rft.au=Feingold, EA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- Ma J, Dempsey AA, Stamatiou D, et al. (2007). "Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects". Atherosclerosis. 191 (1): 63–72. doi:10.1016/j.atherosclerosis.2006.05.032. PMID 16806233.63-72&rft.date=2007&rft_id=info:doi/10.1016/j.atherosclerosis.2006.05.032&rft_id=info:pmid/16806233&rft.aulast=Ma&rft.aufirst=J&rft.au=Dempsey, AA&rft.au=Stamatiou, D&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- Panov KI, Panova TB, Gadal O, et al. (2006). "RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor". Mol. Cell. Biol. 26 (14): 5436–48. doi:10.1128/MCB.00230-06. PMC 1592716. PMID 16809778.5436-48&rft.date=2006&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592716#id-name=PMC&rft_id=info:pmid/16809778&rft_id=info:doi/10.1128/MCB.00230-06&rft.aulast=Panov&rft.aufirst=KI&rft.au=Panova, TB&rft.au=Gadal, O&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592716&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
- Skjelbred CF, Saebø M, Nexø BA, et al. (2006). "Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study". BMC Cancer. 6: 175. doi:10.1186/1471-2407-6-175. PMC 1533843. PMID 16817948.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.1285-92&rft.date=2006&rft_id=https://api.semanticscholar.org/CorpusID:14294292#id-name=S2CID&rft_id=info:pmid/16964243&rft_id=info:doi/10.1038/nbt1240&rft.aulast=Beausoleil&rft.aufirst=SA&rft.au=Villén, J&rft.au=Gerber, SA&rfr_id=info:sid/en.wikipedia.org:CD3EAP" class="Z3988">
External links
edit- Human CAST genome location and CAST gene details page in the UCSC Genome Browser.
- Human CD3EAP genome location and CD3EAP gene details page in the UCSC Genome Browser.