Coiled-coil domain-containing protein 85B is a protein that in humans is encoded by the CCDC85B gene.[5][6][7]

CCDC85B
Identifiers
AliasesCCDC85B, DIPA, coiled-coil domain containing 85B
External IDsOMIM: 605360; MGI: 2147607; HomoloGene: 4989; GeneCards: CCDC85B; OMA:CCDC85B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006848

NM_001243307
NM_198616

RefSeq (protein)

NP_006839

NP_001230236
NP_941018

Location (UCSC)Chr 11: 65.89 – 65.89 MbChr 19: 5.5 – 5.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids. Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro.[7]

Interactions

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CCDC85B has been shown to interact with:

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000175602Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000095098Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Brazas R, Ganem D (Oct 1996). "A cellular homolog of hepatitis delta antigen: implications for viral replication and evolution". Science. 274 (5284): 90–4. Bibcode:1996Sci...274...90B. doi:10.1126/science.274.5284.90. PMID 8810253. S2CID 20743492.90-4&rft.date=1996-10&rft_id=info:doi/10.1126/science.274.5284.90&rft_id=https://api.semanticscholar.org/CorpusID:20743492#id-name=S2CID&rft_id=info:pmid/8810253&rft_id=info:bibcode/1996Sci...274...90B&rft.aulast=Brazas&rft.aufirst=R&rft.au=Ganem, D&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">
  6. ^ Bezy O, Elabd C, Cochet O, Petersen RK, Kristiansen K, Dani C, et al. (Mar 2005). "Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein beta, implicated in adipocyte differentiation". The Journal of Biological Chemistry. 280 (12): 11432–8. doi:10.1074/jbc.M411741200. PMID 15644333.11432-8&rft.date=2005-03&rft_id=info:doi/10.1074/jbc.M411741200&rft_id=info:pmid/15644333&rft.aulast=Bezy&rft.aufirst=O&rft.au=Elabd, C&rft.au=Cochet, O&rft.au=Petersen, RK&rft.au=Kristiansen, K&rft.au=Dani, C&rft.au=Ailhaud, G&rft.au=Amri, EZ&rft_id=https://doi.org/10.1074%2Fjbc.M411741200&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">
  7. ^ a b "Entrez Gene: CCDC85B coiled-coil domain containing 85B".
  8. ^ a b c d Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.1173-8&rft.date=2005-10&rft_id=info:doi/10.1038/nature04209&rft_id=https://api.semanticscholar.org/CorpusID:4427026#id-name=S2CID&rft_id=info:pmid/16189514&rft_id=info:bibcode/2005Natur.437.1173R&rft.aulast=Rual&rft.aufirst=JF&rft.au=Venkatesan, K&rft.au=Hao, T&rft.au=Hirozane-Kishikawa, T&rft.au=Dricot, A&rft.au=Li, N&rft.au=Berriz, GF&rft.au=Gibbons, FD&rft.au=Dreze, M&rft.au=Ayivi-Guedehoussou, N&rft.au=Klitgord, N&rft.au=Simon, C&rft.au=Boxem, M&rft.au=Milstein, S&rft.au=Rosenberg, J&rft.au=Goldberg, DS&rft.au=Zhang, LV&rft.au=Wong, SL&rft.au=Franklin, G&rft.au=Li, S&rft.au=Albala, JS&rft.au=Lim, J&rft.au=Fraughton, C&rft.au=Llamosas, E&rft.au=Cevik, S&rft.au=Bex, C&rft.au=Lamesch, P&rft.au=Sikorski, RS&rft.au=Vandenhaute, J&rft.au=Zoghbi, HY&rft.au=Smolyar, A&rft.au=Bosak, S&rft.au=Sequerra, R&rft.au=Doucette-Stamm, L&rft.au=Cusick, ME&rft.au=Hill, DE&rft.au=Roth, FP&rft.au=Vidal, M&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">
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Further reading

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  • Robertson HD (Oct 1996). "How did replicating and coding RNAs first get together?". Science. 274 (5284): 66–7. Bibcode:1996Sci...274...66R. doi:10.1126/science.274.5284.66. PMID 8848724. S2CID 37715470.66-7&rft.date=1996-10&rft_id=info:doi/10.1126/science.274.5284.66&rft_id=https://api.semanticscholar.org/CorpusID:37715470#id-name=S2CID&rft_id=info:pmid/8848724&rft_id=info:bibcode/1996Sci...274...66R&rft.aulast=Robertson&rft.aufirst=HD&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">
  • Long M, de Souza SJ, Gilbert W (May 1997). "Delta-interacting protein A and the origin of hepatitis delta antigen". Science. 276 (5313): 824–5. doi:10.1126/science.276.5313.824. PMID 9115212.824-5&rft.date=1997-05&rft_id=info:doi/10.1126/science.276.5313.824&rft_id=info:pmid/9115212&rft.aulast=Long&rft.aufirst=M&rft.au=de Souza, SJ&rft.au=Gilbert, W&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">
  • Schumacher B, Schertel C, Wittenburg N, Tuck S, Mitani S, Gartner A, et al. (Feb 2005). "C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage". Cell Death and Differentiation. 12 (2): 153–61. doi:10.1038/sj.cdd.4401539. PMID 15605074.153-61&rft.date=2005-02&rft_id=info:doi/10.1038/sj.cdd.4401539&rft_id=info:pmid/15605074&rft.aulast=Schumacher&rft.aufirst=B&rft.au=Schertel, C&rft.au=Wittenburg, N&rft.au=Tuck, S&rft.au=Mitani, S&rft.au=Gartner, A&rft.au=Conradt, B&rft.au=Shaham, S&rft_id=https://doi.org/10.1038%2Fsj.cdd.4401539&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.1173-8&rft.date=2005-10&rft_id=info:doi/10.1038/nature04209&rft_id=https://api.semanticscholar.org/CorpusID:4427026#id-name=S2CID&rft_id=info:pmid/16189514&rft_id=info:bibcode/2005Natur.437.1173R&rft.aulast=Rual&rft.aufirst=JF&rft.au=Venkatesan, K&rft.au=Hao, T&rft.au=Hirozane-Kishikawa, T&rft.au=Dricot, A&rft.au=Li, N&rft.au=Berriz, GF&rft.au=Gibbons, FD&rft.au=Dreze, M&rft.au=Ayivi-Guedehoussou, N&rft.au=Klitgord, N&rft.au=Simon, C&rft.au=Boxem, M&rft.au=Milstein, S&rft.au=Rosenberg, J&rft.au=Goldberg, DS&rft.au=Zhang, LV&rft.au=Wong, SL&rft.au=Franklin, G&rft.au=Li, S&rft.au=Albala, JS&rft.au=Lim, J&rft.au=Fraughton, C&rft.au=Llamosas, E&rft.au=Cevik, S&rft.au=Bex, C&rft.au=Lamesch, P&rft.au=Sikorski, RS&rft.au=Vandenhaute, J&rft.au=Zoghbi, HY&rft.au=Smolyar, A&rft.au=Bosak, S&rft.au=Sequerra, R&rft.au=Doucette-Stamm, L&rft.au=Cusick, ME&rft.au=Hill, DE&rft.au=Roth, FP&rft.au=Vidal, M&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">
  • Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, et al. (May 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.801-14&rft.date=2006-05&rft_id=https://api.semanticscholar.org/CorpusID:13709685#id-name=S2CID&rft_id=info:pmid/16713569&rft_id=info:doi/10.1016/j.cell.2006.03.032&rft.aulast=Lim&rft.aufirst=J&rft.au=Hao, T&rft.au=Shaw, C&rft.au=Patel, AJ&rft.au=Szabó, G&rft.au=Rual, JF&rft.au=Fisk, CJ&rft.au=Li, N&rft.au=Smolyar, A&rft.au=Hill, DE&rft.au=Barabási, AL&rft.au=Vidal, M&rft.au=Zoghbi, HY&rft_id=https://doi.org/10.1016%2Fj.cell.2006.03.032&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">
  • Du X, Wang Q, Hirohashi Y, Greene MI (Dec 2006). "DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription". Experimental and Molecular Pathology. 81 (3): 184–90. doi:10.1016/j.yexmp.2006.07.008. PMID 17014843.184-90&rft.date=2006-12&rft_id=info:doi/10.1016/j.yexmp.2006.07.008&rft_id=info:pmid/17014843&rft.aulast=Du&rft.aufirst=X&rft.au=Wang, Q&rft.au=Hirohashi, Y&rft.au=Greene, MI&rfr_id=info:sid/en.wikipedia.org:CCDC85B" class="Z3988">