Angela Casini is a medicinal and inorganic chemist who works on metal-based compounds as therapeutic agents. She was awarded the 2012 European Medal for Bio-Inorganic Chemistry and made the 2019 American Chemical Society Inorganic Lecturer.
Angela Casini | |
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Alma mater | University of Florence |
Awards | European Medal for Bio-Inorganic Chemistry |
Scientific career | |
Institutions | Technical University of Munich University of Groningen |
Early life and education
edit[1] She earned her PhD in chemical sciences at the University of Florence in 2004.[2] She was a postdoctoral fellow at the University of Pisa, where she worked on the mechanisms by which metal-complexes that are used as anti-cancer agents activate.[1] She used both spectroscopy, including mass spectrometry imaging, and molecular biology.[1]
Research and career
editAngela Casini joined the École Polytechnique Fédérale de Lausanne as a Principal Investigator in 2008.[3] She moved to the University of Groningen in 2011, where she was made a Rosalind Franklin Fellow.[4] She was made a Chair of Medicinal Chemistry at Cardiff University in 2015, and has served as Director of Postgraduate Teaching from 2018.[5] She spent 2016 as a visiting professor at the Technical University of Munich.
Awards and honours
editHer awards and honours include;
- 2012 European Medal for Bio-Inorganic Chemistry[6]
- 2014 Gordon Research Conference Early Career Investigator[7]
- 2014 Thomson Reuters World's Most Influential Scientific Mind[8]
- 2016 Elected to the Young Academy of Europe[9]
- 2018 Burghausen Diamond of Chemistry Award[10][11]
- 2019 American Chemical Society Inorganic Lectureship Award[12][13]
Selected publications
editHer publications include;
- Casini, Angela (2003). "Carbonic anhydrase inhibitors". Medicinal Research Reviews. 23 (2): 146–189. doi:10.1002/med.10025. PMID 12500287. S2CID 90349277.146-189&rft.date=2003&rft_id=https://api.semanticscholar.org/CorpusID:90349277#id-name=S2CID&rft_id=info:pmid/12500287&rft_id=info:doi/10.1002/med.10025&rft.aulast=Casini&rft.aufirst=Angela&rft_id=https://doi.org/10.1002%2Fmed.10025&rfr_id=info:sid/en.wikipedia.org:Angela Casini" class="Z3988">
- Casini, Angela (2004). "Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH". FEBS Letters. 577 (3): 439–445. doi:10.1016/j.febslet.2004.10.043. PMID 15556624. S2CID 37646843.439-445&rft.date=2004&rft_id=https://api.semanticscholar.org/CorpusID:37646843#id-name=S2CID&rft_id=info:pmid/15556624&rft_id=info:doi/10.1016/j.febslet.2004.10.043&rft.aulast=Casini&rft.aufirst=Angela&rft_id=https://doi.org/10.1016%2Fj.febslet.2004.10.043&rfr_id=info:sid/en.wikipedia.org:Angela Casini" class="Z3988">
- Casini, Angela (2004). "Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition". Journal of Medicinal Chemistry. 47 (3): 550–557. doi:10.1021/jm030912m. PMID 14736236.550-557&rft.date=2004&rft_id=info:doi/10.1021/jm030912m&rft_id=info:pmid/14736236&rft.aulast=Casini&rft.aufirst=Angela&rfr_id=info:sid/en.wikipedia.org:Angela Casini" class="Z3988">
Casini serves on the editorial board of the Journal of Biological Inorganic Chemistry and the Journal of Inorganic Biochemistry.
References
edit- ^ a b c Gabbiani, Chiara; Casini, Angela; Messori, Luigi (2007-03-01). "Gold(III) compounds as anticancer drugs". Gold Bulletin. 40 (1): 73–81. doi:10.1007/BF03215296. ISSN 2190-7579.73-81&rft.date=2007-03-01&rft_id=info:doi/10.1007/BF03215296&rft.issn=2190-7579&rft.aulast=Gabbiani&rft.aufirst=Chiara&rft.au=Casini, Angela&rft.au=Messori, Luigi&rft_id=https://doi.org/10.1007%2FBF03215296&rfr_id=info:sid/en.wikipedia.org:Angela Casini" class="Z3988">
- ^ Medicinal, Professor Angela Casini Chair of; Chemistry, Bioinorganic. "Professor Angela Casini - People". Cardiff University. Retrieved 2019-08-26.
- ^ Casini, Angela; Woods, Benjamin; Wenzel, Margot (2017-12-18). "The Promise of Self-Assembled 3D Supramolecular Coordination Complexes for Biomedical Applications". Inorganic Chemistry. 56 (24): 14715–14729. doi:10.1021/acs.inorgchem.7b02599. ISSN 0020-1669. PMID 29172467.14715-14729&rft.date=2017-12-18&rft.issn=0020-1669&rft_id=info:pmid/29172467&rft_id=info:doi/10.1021/acs.inorgchem.7b02599&rft.aulast=Casini&rft.aufirst=Angela&rft.au=Woods, Benjamin&rft.au=Wenzel, Margot&rft_id=https://doi.org/10.1021%2Facs.inorgchem.7b02599&rfr_id=info:sid/en.wikipedia.org:Angela Casini" class="Z3988">
- ^ "Institute for Advanced Study (IAS): Casini, Angela". www.ias.tum.de. Retrieved 2019-08-26.
- ^ "The School of Chemistry welcomes new staff member Professor Angela Casini". Cardiff University. Retrieved 2019-08-26.
- ^ "EuroBIC". www.bioinorganic-chemistry.org. Retrieved 2019-08-26.
- ^ "2014 Metals in Medicine Conference GRC". www.grc.org. Retrieved 2019-08-26.
- ^ "Angela Casini". metallomics2017.univie.ac.at. Retrieved 2019-08-26.
- ^ "Angela Casini – Young Academy of Europe". 18 December 2016. Retrieved 2019-08-26.
- ^ "Burghausen Chemistry Award for Angela Casini". www.tum.de. Retrieved 2019-08-26.
- ^ "Burghausen Chemistry Award for Angela Casini". www.tum.de. Retrieved 2019-08-26.
- ^ "Angela Casini Receives 2019 Inorganic Chemistry Lectureship Award". ACS Axial. 2019-03-12. Retrieved 2019-08-26.
- ^ Medicinal, Professor Angela Casini Chair of; Chemistry, Bioinorganic; PGT, Director of. "Prof Angela Casini wins 2019 Inorganic Chemistry Lectureship Award". Cardiff University. Retrieved 2019-08-26.