α-Santalene synthase (EC 4.2.3.82) is an enzyme with systematic name (2E,6E)-farnesyl diphosphate lyase (cyclizing, ( )-α-santalene-forming).[1] This enzyme catalyses the following chemical reaction
| α-santalene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.82 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate ( )-α-santalene diphosphate
The enzyme synthesizes a mixture of sesquiterpenes.
References
edit- ^ Jones CG, Moniodis J, Zulak KG, Scaffidi A, Plummer JA, Ghisalberti EL, Barbour EL, Bohlmann J (May 2011). "Sandalwood fragrance biosynthesis involves sesquiterpene synthases of both the terpene synthase (TPS)-a and TPS-b subfamilies, including santalene synthases". The Journal of Biological Chemistry. 286 (20): 17445–54. doi:10.1074/jbc.m111.231787. PMC 3093818. PMID 21454632.17445-54&rft.date=2011-05&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093818#id-name=PMC&rft_id=info:pmid/21454632&rft_id=info:doi/10.1074/jbc.m111.231787&rft.aulast=Jones&rft.aufirst=CG&rft.au=Moniodis, J&rft.au=Zulak, KG&rft.au=Scaffidi, A&rft.au=Plummer, JA&rft.au=Ghisalberti, EL&rft.au=Barbour, EL&rft.au=Bohlmann, J&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093818&rfr_id=info:sid/en.wikipedia.org:Alpha-santalene synthase" class="Z3988">
External links
edit- Alpha-santalene synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
