Alkylglycerone phosphate synthase (EC 2.5.1.26 , alkyldihydroxyacetonephosphate synthase , alkyldihydroxyacetone phosphate synthetase , alkyl DHAP synthetase , alkyl-DHAP , dihydroxyacetone-phosphate acyltransferase , DHAP-AT ) is an enzyme associated with Type 3 Rhizomelic chondrodysplasia punctata .[ 1] [ 2] This enzyme catalyses the following chemical reaction
1-acyl-glycerone 3-phosphate a long-chain alcohol
⇌
{\displaystyle \rightleftharpoons }
an alkyl-glycerone 3-phosphate a long-chain acid anion
^ Brown AJ, Snyder F (August 1982). "Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism" . The Journal of Biological Chemistry . 257 (15): 8835– 9. doi :10.1016/S0021-9258(18)34205-4 . PMID 7096336 . 8835- 9&rft.date=1982-08&rft_id=info:doi/10.1016/S0021-9258(18)34205-4&rft_id=info:pmid/7096336&rft.aulast=Brown&rft.aufirst=AJ&rft.au=Snyder, F&rft_id=https://doi.org/10.1016%2FS0021-9258%2818%2934205-4&rfr_id=info:sid/en.wikipedia.org:Alkylglycerone phosphate synthase" class="Z3988">
^ Wykle RL, Plantadosi C, Snyder F (May 1972). "The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor" . The Journal of Biological Chemistry . 247 (9): 2944– 8. doi :10.1016/S0021-9258(19)45301-5 . PMID 4401994 . 2944- 8&rft.date=1972-05&rft_id=info:doi/10.1016/S0021-9258(19)45301-5&rft_id=info:pmid/4401994&rft.aulast=Wykle&rft.aufirst=RL&rft.au=Plantadosi, C&rft.au=Snyder, F&rft_id=https://doi.org/10.1016%2FS0021-9258%2819%2945301-5&rfr_id=info:sid/en.wikipedia.org:Alkylglycerone phosphate synthase" class="Z3988">