Alkylglycerone phosphate synthase

Alkylglycerone phosphate synthase (EC 2.5.1.26, alkyldihydroxyacetonephosphate synthase, alkyldihydroxyacetone phosphate synthetase, alkyl DHAP synthetase, alkyl-DHAP, dihydroxyacetone-phosphate acyltransferase, DHAP-AT) is an enzyme associated with Type 3 Rhizomelic chondrodysplasia punctata.[1][2] This enzyme catalyses the following chemical reaction

alkylglycerone-phosphate synthase
Identifiers
EC no.2.5.1.26
CAS no.64060-42-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
alkylglycerone phosphate synthase
Identifiers
SymbolAGPS
NCBI gene8540
HGNC327
OMIM603051
RefSeqNM_003659
UniProtO00116
Other data
EC number2.5.1.26
LocusChr. 2 q31
Search for
StructuresSwiss-model
DomainsInterPro
1-acyl-glycerone 3-phosphate a long-chain alcohol an alkyl-glycerone 3-phosphate a long-chain acid anion

References

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  1. ^ Brown AJ, Snyder F (August 1982). "Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism". The Journal of Biological Chemistry. 257 (15): 8835–9. doi:10.1016/S0021-9258(18)34205-4. PMID 7096336.8835-9&rft.date=1982-08&rft_id=info:doi/10.1016/S0021-9258(18)34205-4&rft_id=info:pmid/7096336&rft.aulast=Brown&rft.aufirst=AJ&rft.au=Snyder, F&rft_id=https://doi.org/10.1016%2FS0021-9258%2818%2934205-4&rfr_id=info:sid/en.wikipedia.org:Alkylglycerone phosphate synthase" class="Z3988">
  2. ^ Wykle RL, Plantadosi C, Snyder F (May 1972). "The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor". The Journal of Biological Chemistry. 247 (9): 2944–8. doi:10.1016/S0021-9258(19)45301-5. PMID 4401994.2944-8&rft.date=1972-05&rft_id=info:doi/10.1016/S0021-9258(19)45301-5&rft_id=info:pmid/4401994&rft.aulast=Wykle&rft.aufirst=RL&rft.au=Plantadosi, C&rft.au=Snyder, F&rft_id=https://doi.org/10.1016%2FS0021-9258%2819%2945301-5&rfr_id=info:sid/en.wikipedia.org:Alkylglycerone phosphate synthase" class="Z3988">
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