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Acidic leucine-rich nuclear phosphoprotein 32 family member A

(Redirected from ANP32A)

Acidic leucine-rich nuclear phosphoprotein 32 family member A is a protein that in humans is encoded by the ANP32A gene.[5][6][7] It is one of the targets of an oncomiR, MIRN21.

ANP32A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesANP32A, C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32, acidic nuclear phosphoprotein 32 family member A
External IDsOMIM: 600832; MGI: 108447; HomoloGene: 133783; GeneCards: ANP32A; OMA:ANP32A - orthologs
Orthologs
SpeciesHumanMouse
Entrez

8125

11737

Ensembl

ENSG00000140350

ENSMUSG00000032249

UniProt

P39687

O35381

RefSeq (mRNA)

NM_006305

NM_009672

RefSeq (protein)

NP_006296

NP_033802

Location (UCSC)Chr 15: 68.78 – 68.82 MbChr 9: 62.25 – 62.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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Acidic leucine-rich nuclear phosphoprotein 32 family member A has been shown to interact with MAP1B,[8] TAF1A[9] and Protein SET.[9][10]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140350 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032249 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chen TH, Brody JR, Romantsev FE, Yu JG, Kayler AE, Voneiff E, Kuhajda FP, Pasternack GR (March 1997). "Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci". Mol Biol Cell. 7 (12): 2045–56. doi:10.1091/mbc.7.12.2045. PMC 276049. PMID 8970164.2045-56&rft.date=1997-03&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC276049#id-name=PMC&rft_id=info:pmid/8970164&rft_id=info:doi/10.1091/mbc.7.12.2045&rft.aulast=Chen&rft.aufirst=TH&rft.au=Brody, JR&rft.au=Romantsev, FE&rft.au=Yu, JG&rft.au=Kayler, AE&rft.au=Voneiff, E&rft.au=Kuhajda, FP&rft.au=Pasternack, GR&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC276049&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  6. ^ Ulitzur N, Humbert M, Pfeffer SR (June 1997). "Mapmodulin: a possible modulator of the interaction of microtubule-associated proteins with microtubules". Proc Natl Acad Sci U S A. 94 (10): 5084–9. Bibcode:1997PNAS...94.5084U. doi:10.1073/pnas.94.10.5084. PMC 24635. PMID 9144194.5084-9&rft.date=1997-06&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC24635#id-name=PMC&rft_id=info:pmid/9144194&rft_id=info:doi/10.1073/pnas.94.10.5084&rft_id=info:bibcode/1997PNAS...94.5084U&rft.aulast=Ulitzur&rft.aufirst=N&rft.au=Humbert, M&rft.au=Pfeffer, SR&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC24635&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  7. ^ "Entrez Gene: ANP32A Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A".
  8. ^ Opal P, Garcia Jesus J, Propst Friedrich, Matilla Antoni, Orr Harry T, Zoghbi Huda Y (September 2003). "Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis". J. Biol. Chem. 278 (36): 34691–9. doi:10.1074/jbc.M302785200. ISSN 0021-9258. PMID 12807913.34691-9&rft.date=2003-09&rft.issn=0021-9258&rft_id=info:pmid/12807913&rft_id=info:doi/10.1074/jbc.M302785200&rft.aulast=Opal&rft.aufirst=Puneet&rft.au=Garcia Jesus J&rft.au=Propst Friedrich&rft.au=Matilla Antoni&rft.au=Orr Harry T&rft.au=Zoghbi Huda Y&rft_id=https://doi.org/10.1074%2Fjbc.M302785200&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  9. ^ a b Seo SB, McNamara P, Heo S, Turner A, Lane W S, Chakravarti D (January 2001). "Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein". Cell. 104 (1): 119–30. doi:10.1016/S0092-8674(01)00196-9. ISSN 0092-8674. PMID 11163245.119-30&rft.date=2001-01&rft.issn=0092-8674&rft_id=info:pmid/11163245&rft_id=info:doi/10.1016/S0092-8674(01)00196-9&rft.aulast=Seo&rft.aufirst=S B&rft.au=McNamara P&rft.au=Heo S&rft.au=Turner A&rft.au=Lane W S&rft.au=Chakravarti D&rft_id=https://doi.org/10.1016%2FS0092-8674%2801%2900196-9&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  10. ^ Fan Z, Beresford Paul J, Zhang Dong, Lieberman Judy (April 2002). "HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Mol. Cell. Biol. 22 (8): 2810–20. doi:10.1128/MCB.22.8.2810-2820.2002. ISSN 0270-7306. PMC 133744. PMID 11909973.2810-20&rft.date=2002-04&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC133744#id-name=PMC&rft.issn=0270-7306&rft_id=info:pmid/11909973&rft_id=info:doi/10.1128/MCB.22.8.2810-2820.2002&rft.aulast=Fan&rft.aufirst=Zusen&rft.au=Beresford Paul J&rft.au=Zhang Dong&rft.au=Lieberman Judy&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC133744&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">

Further reading

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  • Matilla A, Radrizzani M (2005). "The Anp32 family of proteins containing leucine-rich repeats". Cerebellum. 4 (1): 7–18. doi:10.1080/14734220410019020. PMID 15895553. S2CID 39153579.7-18&rft.date=2005&rft_id=https://api.semanticscholar.org/CorpusID:39153579#id-name=S2CID&rft_id=info:pmid/15895553&rft_id=info:doi/10.1080/14734220410019020&rft.aulast=Matilla&rft.aufirst=A&rft.au=Radrizzani, M&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Schraven B, Kirchgessner H, Gaber B, et al. (1991). "A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56lck and pp32, a possible common substrate". Eur. J. Immunol. 21 (10): 2469–77. doi:10.1002/eji.1830211025. PMID 1655467. S2CID 24230538.2469-77&rft.date=1991&rft_id=https://api.semanticscholar.org/CorpusID:24230538#id-name=S2CID&rft_id=info:pmid/1655467&rft_id=info:doi/10.1002/eji.1830211025&rft.aulast=Schraven&rft.aufirst=B&rft.au=Kirchgessner, H&rft.au=Gaber, B&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.1–2&rft.pages=171-4&rft.date=1994&rft_id=info:doi/10.1016/0378-1119(94)90802-8&rft_id=info:pmid/8125298&rft.aulast=Maruyama&rft.aufirst=K&rft.au=Sugano, S&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Vaesen M, Barnikol-Watanabe S, Götz H, et al. (1994). "Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII". Biol. Chem. Hoppe-Seyler. 375 (2): 113–26. doi:10.1515/bchm3.1994.375.2.113. PMID 8192856.113-26&rft.date=1994&rft_id=info:doi/10.1515/bchm3.1994.375.2.113&rft_id=info:pmid/8192856&rft.aulast=Vaesen&rft.aufirst=M&rft.au=Barnikol-Watanabe, S&rft.au=Götz, H&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Fink TM, Vaesen M, Kratzin HD, et al. (1996). "Localization of the gene encoding the putative human HLA class II associated protein (PHAPI) to chromosome 15q22.3-q23 by fluorescence in situ hybridization". Genomics. 29 (1): 309–10. doi:10.1006/geno.1995.1257. PMID 8530098.309-10&rft.date=1996&rft_id=info:doi/10.1006/geno.1995.1257&rft_id=info:pmid/8530098&rft.aulast=Fink&rft.aufirst=TM&rft.au=Vaesen, M&rft.au=Kratzin, HD&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.107-13&rft.date=1996&rft_id=info:doi/10.1006/abio.1996.0138&rft_id=info:pmid/8619474&rft.aulast=Andersson&rft.aufirst=B&rft.au=Wentland, MA&rft.au=Ricafrente, JY&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Li M, Makkinje A, Damuni Z (1996). "Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A". Biochemistry. 35 (22): 6998–7002. doi:10.1021/bi960581y. PMID 8679524.6998-7002&rft.date=1996&rft_id=info:doi/10.1021/bi960581y&rft_id=info:pmid/8679524&rft.aulast=Li&rft.aufirst=M&rft.au=Makkinje, A&rft.au=Damuni, Z&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.353-8&rft.date=1997&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139146#id-name=PMC&rft_id=info:pmid/9110174&rft_id=info:doi/10.1101/gr.7.4.353&rft.aulast=Yu&rft.aufirst=W&rft.au=Andersson, B&rft.au=Worley, KC&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139146&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Matilla A, Koshy BT, Cummings CJ, et al. (1997). "The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1". Nature. 389 (6654): 974–8. Bibcode:1997Natur.389..974M. doi:10.1038/40159. PMID 9353121. S2CID 4383708.974-8&rft.date=1997&rft_id=info:doi/10.1038/40159&rft_id=https://api.semanticscholar.org/CorpusID:4383708#id-name=S2CID&rft_id=info:pmid/9353121&rft_id=info:bibcode/1997Natur.389..974M&rft.aulast=Matilla&rft.aufirst=A&rft.au=Koshy, BT&rft.au=Cummings, CJ&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.1–2&rft.pages=149-56&rft.date=1997&rft_id=info:doi/10.1016/S0378-1119(97)00411-3&rft_id=info:pmid/9373149&rft.aulast=Suzuki&rft.aufirst=Y&rft.au=Yoshitomo-Nakagawa, K&rft.au=Maruyama, K&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Kadkol SS, Brody JR, Pevsner J, et al. (1999). "Modulation of oncogenic potential by alternative gene use in human prostate cancer". Nat. Med. 5 (3): 275–9. doi:10.1038/6488. PMID 10086381. S2CID 24559649.275-9&rft.date=1999&rft_id=https://api.semanticscholar.org/CorpusID:24559649#id-name=S2CID&rft_id=info:pmid/10086381&rft_id=info:doi/10.1038/6488&rft.aulast=Kadkol&rft.aufirst=SS&rft.au=Brody, JR&rft.au=Pevsner, J&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Brody JR, Kadkol SS, Mahmoud MA, et al. (1999). "Identification of sequences required for inhibition of oncogene-mediated transformation by pp32". J. Biol. Chem. 274 (29): 20053–5. doi:10.1074/jbc.274.29.20053. PMID 10400610.20053-5&rft.date=1999&rft_id=info:doi/10.1074/jbc.274.29.20053&rft_id=info:pmid/10400610&rft.aulast=Brody&rft.aufirst=JR&rft.au=Kadkol, SS&rft.au=Mahmoud, MA&rft_id=https://doi.org/10.1074%2Fjbc.274.29.20053&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Brennan CM, Gallouzi IE, Steitz JA (2000). "Protein ligands to HuR modulate its interaction with target mRNAs in vivo". J. Cell Biol. 151 (1): 1–14. doi:10.1083/jcb.151.1.1. PMC 2189805. PMID 11018049.1-14&rft.date=2000&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189805#id-name=PMC&rft_id=info:pmid/11018049&rft_id=info:doi/10.1083/jcb.151.1.1&rft.aulast=Brennan&rft.aufirst=CM&rft.au=Gallouzi, IE&rft.au=Steitz, JA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189805&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Seo SB, McNamara P, Heo S, et al. (2001). "Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein". Cell. 104 (1): 119–30. doi:10.1016/S0092-8674(01)00196-9. PMID 11163245.119-30&rft.date=2001&rft_id=info:doi/10.1016/S0092-8674(01)00196-9&rft_id=info:pmid/11163245&rft.aulast=Seo&rft.aufirst=SB&rft.au=McNamara, P&rft.au=Heo, S&rft_id=https://doi.org/10.1016%2FS0092-8674%2801%2900196-9&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Bai J, Brody JR, Kadkol SS, Pasternack GR (2001). "Tumor suppression and potentiation by manipulation of pp32 expression". Oncogene. 20 (17): 2153–60. doi:10.1038/sj.onc.1204294. PMID 11360199.2153-60&rft.date=2001&rft_id=info:doi/10.1038/sj.onc.1204294&rft_id=info:pmid/11360199&rft.aulast=Bai&rft.aufirst=J&rft.au=Brody, JR&rft.au=Kadkol, SS&rft.au=Pasternack, GR&rft_id=https://doi.org/10.1038%2Fsj.onc.1204294&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Beresford PJ, Zhang D, Oh DY, et al. (2001). "Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks". J. Biol. Chem. 276 (46): 43285–93. doi:10.1074/jbc.M108137200. PMID 11555662.43285-93&rft.date=2001&rft_id=info:doi/10.1074/jbc.M108137200&rft_id=info:pmid/11555662&rft.aulast=Beresford&rft.aufirst=PJ&rft.au=Zhang, D&rft.au=Oh, DY&rft_id=https://doi.org/10.1074%2Fjbc.M108137200&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
  • Gallouzi IE, Steitz JA (2001). "Delineation of mRNA export pathways by the use of cell-permeable peptides". Science. 294 (5548): 1895–901. Bibcode:2001Sci...294.1895G. doi:10.1126/science.1064693. PMID 11729309. S2CID 43726887.1895-901&rft.date=2001&rft_id=info:doi/10.1126/science.1064693&rft_id=https://api.semanticscholar.org/CorpusID:43726887#id-name=S2CID&rft_id=info:pmid/11729309&rft_id=info:bibcode/2001Sci...294.1895G&rft.aulast=Gallouzi&rft.aufirst=IE&rft.au=Steitz, JA&rfr_id=info:sid/en.wikipedia.org:Acidic leucine-rich nuclear phosphoprotein 32 family member A" class="Z3988">
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