Wikipedia

ADAMTSL4

(Redirected from ADAMTSL4 (gene))

ADAMTS-like protein 4 is a protein that in humans is encoded by the ADAMTSL4 gene.[5][6]

ADAMTSL4
Identifiers
AliasesADAMTSL4, ADAMTSL-4, ECTOL2, TSRC1, ADAMTS like 4
External IDsOMIM: 610113; MGI: 2389008; HomoloGene: 23141; GeneCards: ADAMTSL4; OMA:ADAMTSL4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

54507

229595

Ensembl

ENSG00000143382

ENSMUSG00000015850

UniProt

Q6UY14

Q80T21

RefSeq (mRNA)

NM_001288607
NM_001288608
NM_019032
NM_025008
NM_001378596

NM_001301705
NM_144899

RefSeq (protein)

NP_001275536
NP_001275537
NP_061905
NP_079284
NP_001365525

NP_001288634
NP_659148

Location (UCSC)Chr 1: 150.55 – 150.56 MbChr 3: 95.58 – 95.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143382 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015850 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Buchner DA, Meisler MH (Mar 2003). "TSRC1, a widely expressed gene containing seven thrombospondin type I repeats". Gene. 307: 23–30. doi:10.1016/S0378-1119(03)00423-2. PMID 12706885.23-30&rft.date=2003-03&rft_id=info:doi/10.1016/S0378-1119(03)00423-2&rft_id=info:pmid/12706885&rft.aulast=Buchner&rft.aufirst=DA&rft.au=Meisler, MH&rfr_id=info:sid/en.wikipedia.org:ADAMTSL4" class="Z3988">
  6. ^ a b "Entrez Gene: ADAMTSL4 ADAMTS-like 4".

Further reading

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  • Adams JC, Tucker RP (Jun 2000). "The thrombospondin type 1 repeat (TSR) superfamily: diverse proteins with related roles in neuronal development". Developmental Dynamics. 218 (2): 280–299. doi:10.1002/(SICI)1097-0177(200006)218:2<280::AID-DVDY4>3.0.CO;2-0. PMID 10842357.280-299&rft.date=2000-06&rft_id=info:doi/10.1002/(SICI)1097-0177(200006)218:2<280::AID-DVDY4>3.0.CO;2-0&rft_id=info:pmid/10842357&rft.aulast=Adams&rft.aufirst=JC&rft.au=Tucker, RP&rft_id=https://doi.org/10.1002%2F%28SICI%291097-0177%28200006%29218%3A2%3C280%3A%3AAID-DVDY4%3E3.0.CO%3B2-0&rfr_id=info:sid/en.wikipedia.org:ADAMTSL4" class="Z3988">
  • Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.791-806&rft.date=1996-09&rft_id=info:doi/10.1101/gr.6.9.791&rft_id=info:pmid/8889548&rft.aulast=Bonaldo&rft.aufirst=MF&rft.au=Lennon, G&rft.au=Soares, MB&rft_id=https://doi.org/10.1101%2Fgr.6.9.791&rfr_id=info:sid/en.wikipedia.org:ADAMTSL4" class="Z3988">
  • Dias Neto E, Correa RG, Verjovski-Almeida S, Briones MR, Nagai MA, da Silva W, Zago MA, Bordin S, Costa FF, Goldman GH, Carvalho AF, Matsukuma A, Baia GS, Simpson DH, Brunstein A, de Oliveira PS, Bucher P, Jongeneel CV, O'Hare MJ, Soares F, Brentani RR, Reis LF, de Souza SJ, Simpson AJ (Mar 2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proceedings of the National Academy of Sciences of the United States of America. 97 (7): 3491–3496. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.3491-3496&rft.date=2000-03&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC16267#id-name=PMC&rft_id=info:pmid/10737800&rft_id=info:doi/10.1073/pnas.97.7.3491&rft_id=info:bibcode/2000PNAS...97.3491D&rft.aulast=Dias Neto&rft.aufirst=E&rft.au=Correa, RG&rft.au=Verjovski-Almeida, S&rft.au=Briones, MR&rft.au=Nagai, MA&rft.au=da Silva, W&rft.au=Zago, MA&rft.au=Bordin, S&rft.au=Costa, FF&rft.au=Goldman, GH&rft.au=Carvalho, AF&rft.au=Matsukuma, A&rft.au=Baia, GS&rft.au=Simpson, DH&rft.au=Brunstein, A&rft.au=de Oliveira, PS&rft.au=Bucher, P&rft.au=Jongeneel, CV&rft.au=O'Hare, MJ&rft.au=Soares, F&rft.au=Brentani, RR&rft.au=Reis, LF&rft.au=de Souza, SJ&rft.au=Simpson, AJ&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC16267&rfr_id=info:sid/en.wikipedia.org:ADAMTSL4" class="Z3988">
  • Wan D, Gong Y, Qin W, Zhang P, Li J, Wei L, Zhou X, Li H, Qiu X, Zhong F, He L, Yu J, Yao G, Jiang H, Qian L, Yu Y, Shu H, Chen X, Xu H, Guo M, Pan Z, Chen Y, Ge C, Yang S, Gu J (Nov 2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proceedings of the National Academy of Sciences of the United States of America. 101 (44): 15724–15729. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.15724-15729&rft.date=2004-11&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524842#id-name=PMC&rft_id=info:pmid/15498874&rft_id=info:doi/10.1073/pnas.0404089101&rft_id=info:bibcode/2004PNAS..10115724W&rft.aulast=Wan&rft.aufirst=D&rft.au=Gong, Y&rft.au=Qin, W&rft.au=Zhang, P&rft.au=Li, J&rft.au=Wei, L&rft.au=Zhou, X&rft.au=Li, H&rft.au=Qiu, X&rft.au=Zhong, F&rft.au=He, L&rft.au=Yu, J&rft.au=Yao, G&rft.au=Jiang, H&rft.au=Qian, L&rft.au=Yu, Y&rft.au=Shu, H&rft.au=Chen, X&rft.au=Xu, H&rft.au=Guo, M&rft.au=Pan, Z&rft.au=Chen, Y&rft.au=Ge, C&rft.au=Yang, S&rft.au=Gu, J&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524842&rfr_id=info:sid/en.wikipedia.org:ADAMTSL4" class="Z3988">
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.1173-1178&rft.date=2005-10&rft_id=info:doi/10.1038/nature04209&rft_id=https://api.semanticscholar.org/CorpusID:4427026#id-name=S2CID&rft_id=info:pmid/16189514&rft_id=info:bibcode/2005Natur.437.1173R&rft.aulast=Rual&rft.aufirst=JF&rft.au=Venkatesan, K&rft.au=Hao, T&rft.au=Hirozane-Kishikawa, T&rft.au=Dricot, A&rft.au=Li, N&rft.au=Berriz, GF&rft.au=Gibbons, FD&rft.au=Dreze, M&rft.au=Ayivi-Guedehoussou, N&rft.au=Klitgord, N&rft.au=Simon, C&rft.au=Boxem, M&rft.au=Milstein, S&rft.au=Rosenberg, J&rft.au=Goldberg, DS&rft.au=Zhang, LV&rft.au=Wong, SL&rft.au=Franklin, G&rft.au=Li, S&rft.au=Albala, JS&rft.au=Lim, J&rft.au=Fraughton, C&rft.au=Llamosas, E&rft.au=Cevik, S&rft.au=Bex, C&rft.au=Lamesch, P&rft.au=Sikorski, RS&rft.au=Vandenhaute, J&rft.au=Zoghbi, HY&rft.au=Smolyar, A&rft.au=Bosak, S&rft.au=Sequerra, R&rft.au=Doucette-Stamm, L&rft.au=Cusick, ME&rft.au=Hill, DE&rft.au=Roth, FP&rft.au=Vidal, M&rfr_id=info:sid/en.wikipedia.org:ADAMTSL4" class="Z3988">
  • Liu T, Qian WJ, Gritsenko MA, Camp DG, Monroe ME, Moore RJ, Smith RD (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". Journal of Proteome Research. 4 (6): 2070–2080. doi:10.1021/pr0502065. PMC 1850943. PMID 16335952.2070-2080&rft.date=2006&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850943#id-name=PMC&rft_id=info:pmid/16335952&rft_id=info:doi/10.1021/pr0502065&rft.aulast=Liu&rft.aufirst=T&rft.au=Qian, WJ&rft.au=Gritsenko, MA&rft.au=Camp, DG&rft.au=Monroe, ME&rft.au=Moore, RJ&rft.au=Smith, RD&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850943&rfr_id=info:sid/en.wikipedia.org:ADAMTSL4" class="Z3988">
  • Liu J, Guo Q, Chen B, Yu Y, Lu H, Li YY (Jan 2006). "Cathepsin B and its interacting proteins, bikunin and TSRC1, correlate with TNF-induced apoptosis of ovarian cancer cells OV-90". FEBS Letters. 580 (1): 245–250. doi:10.1016/j.febslet.2005.12.005. PMID 16364318. S2CID 8768006.245-250&rft.date=2006-01&rft_id=https://api.semanticscholar.org/CorpusID:8768006#id-name=S2CID&rft_id=info:pmid/16364318&rft_id=info:doi/10.1016/j.febslet.2005.12.005&rft.aulast=Liu&rft.aufirst=J&rft.au=Guo, Q&rft.au=Chen, B&rft.au=Yu, Y&rft.au=Lu, H&rft.au=Li, YY&rfr_id=info:sid/en.wikipedia.org:ADAMTSL4" class="Z3988">
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