Date Opponent Site Result Attendance Source September 23 Tulsa W 23–1415,015 [ 3]
September 30 at No. 7 Stanford L 7–5535,000 [ 4]
October 8 Nevada Kezar Stadium San Francisco, CA W 66–611,112 [ 5]
October 14 Saint Mary's Kezar Stadium San Francisco, CA W 33–720,000 [ 6]
October 20 San Jose State Kezar Stadium San Francisco, CA W 27–015,208 [ 7]
October 28 at Fordham L 14–2111,000 [ 8]
November 4 at Denver W 24–69,738 [ 9]
November 11 Santa Clara Kezar Stadium San Francisco, CA W 27–613,567 [ 10]
November 18 at No. 4 California L 7–1314,000 [ 11]
November 26 Detroit Kezar Stadium San Francisco, CA W 35–1311,783 [ 12] [ 13]
December 3 at No. 20 Loyola (CA) L 28–413,000 [ 14]
Rankings from AP Poll released prior to the game
^ "1950 San Francisco Dons Schedule and Results" . SR/College Football . Sports Reference LLC. Retrieved July 23, 2018 .
^ Official Collegiate Football Record Book . National Collegiate Athletic Association. 1951. p. 38.
^ Bill Mulligan (September 24, 1950). "Dons Zip By Tulsa: Matson on Spree In 23-14 Win" . The San Francisco Examiner . p. 20 – via Newspapers.com .
^ Bob Brachman (October 1, 1950). "Stanford Steamrollers USF, 55-7! Thumping by Indians Worst in Don History; Cards Shut Gates of Mercy; 35,000 See Matson Completely Bottled Up" . The San Francisco Examiner . pp. 22, 26 – via Newspapers.com .
^ Bob Brachman (October 9, 1950). "Dons Go Wild, 66-6: USF Buries Nevada; Scudero, Matson Spark Onslaught" . The San Francisco Examiner . p. 30 – via Newspapers.com .
^ Harry Borba (October 16, 1950). "Don Men Slug St. Mary's Boys, 33-7: Gaels' Johnson Gains -- But Matson Reigns; USF Makes It 4 in a Row Over Old Foe; Bombiani Scoots 79 for Moraga Tally" . San Francisco Examiner . pp. 36, 39 – via Newspapers.com .
^ Harry Borba (October 21, 1950). "Too Much Class! USF 27, San Jose 0: Dons Put On Show; Matson Goes Over For Two Scores" . The San Francisco Examiner . pp. 17, 18 – via Newspapers.com .
^ Mulligan, Bill (October 29, 1950). "Rams' Rally Whips Dons!" . San Francisco Examiner . San Francisco, Calif. p. 26 – via Newspapers.com .
^ Bill Mulligan (November 5, 1950). "Matson, Barni Lead Dons To 24-6 Win Over Denver" . The San Francisco Examiner . p. 28 – via Newspapers.com .
^ "USF Drives Past Santa Clara 27-6" . The Press Democrat . Santa Rosa, California. November 13, 1950. p. 8 – via Newspapers.com .
^ Bob Brachman (November 19, 1950). "Bears Nudge Dons, 13-7, in Final Quarter: Interception Sets Up Cal's Winning Score; Solari Rambles 35 for TD on Fumble Recovery; Barni Gallops 85 to Tally" . The San Francisco Examiner . pp. 24, 27 – via Newspapers.com .
^ "Titans Run Down Badly on Coast" . Detroit Free Press . November 27, 1950. p. 30 – via Newspapers.com .
^ "Brown Passes Hilltoppers To 35-13 Win Over Detroit" . Oakland Tribune . November 27, 1950. p. 32 – via Newspapers.com .
^ Jack Geyer (December 4, 1950). "Supercharged Lions Roar to 40-28 Victory Over Dons" . Los Angeles Times . pp. IV-1, IV-4 – via Newspapers.com .