16BO133 is a SARS-like coronavirus (SL-COV) which was found in the greater horseshoe bat in South Korea. It was published in 2019 and its genome was completely sequenced. The sequenced Korean SARSr-CoV strain belongs to the severe acute respiratory syndrome coronavirus 1, and its genome sequence similarity is 82.8%.
| 16BO133 | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | Sarbecovirus |
| Species: | |
| Strain: | 16BO133
|
Discovery
editThe 16BO133 virus was discovered in the oral cavity of the greater horseshoe bat in 2016. The genome of this virus strain is 29075 nt. Among SARSr-CoVs, 16BO133 is the closest to the JTMC15 virus, which was published in 2016 and discovered in Jilin, China, with a genome nucleic acid sequence similarity of 98.3%. Compared with other SARSr-CoVs, these two viruses have the ORF8 strain due to a frameshift mutation at the end of ORF7b.[1][2] The similarity of the genome nucleic acid sequence of 16BO133 virus and SARS-CoV is 82.8%.[3]
Although other SARSr-CoV strains have been found in Korea in the past (B15-21 virus, etc.), none of them have been sequenced.[4] The 16BO133 virus is the first Korean SARSr-CoV strain to be completely sequenced.[1]
Phylogenetic
editA phylogenetic tree based on whole-genome sequences of SARS-CoV-1 and related coronaviruses is:
See also
editReferences
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- ^ Xu L, Zhang F, Yang W, Jiang T, Lu G, He B, et al. (2016). "Detection and characterization of diverse alpha- and betacoronaviruses from bats in China". Virol Sin. 31 (1): 69–77. doi:10.1007/s12250-016-3727-3. PMC 7090707. PMID 26847648.69-77&rft.date=2016&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090707#id-name=PMC&rft_id=info:pmid/26847648&rft_id=info:doi/10.1007/s12250-016-3727-3&rft.aulast=Xu&rft.aufirst=L&rft.au=Zhang, F&rft.au=Yang, W&rft.au=Jiang, T&rft.au=Lu, G&rft.au=He, B&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090707&rfr_id=info:sid/en.wikipedia.org:16BO133" class="Z3988">
- ^ Na EJ, Lee SY, Kim HJ, Oem JK (2021). "Comparative genetic analyses of Korean bat coronaviruses with SARS-CoV and the newly emerged SARS-CoV-2". J Vet Sci. 22 (1): e12. doi:10.4142/jvs.2021.22.e12. PMC 7850784. PMID 33522164.
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- ^ Kim, Yongkwan; Son, Kidong; Kim, Young-Sik; Lee, Sook-Young; Jheong, Weonhwa; Oem, Jae-Ku (2019). "Complete genome analysis of a SARS-like bat coronavirus identified in the Republic of Korea". Virus Genes. 55 (4): 545–549. doi:10.1007/s11262-019-01668-w. PMC 7089380. PMID 31076983.545-549&rft.date=2019&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089380#id-name=PMC&rft_id=info:pmid/31076983&rft_id=info:doi/10.1007/s11262-019-01668-w&rft.aulast=Kim&rft.aufirst=Yongkwan&rft.au=Son, Kidong&rft.au=Kim, Young-Sik&rft.au=Lee, Sook-Young&rft.au=Jheong, Weonhwa&rft.au=Oem, Jae-Ku&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089380&rfr_id=info:sid/en.wikipedia.org:16BO133" class="Z3988">
- ^ Xu, L; Zhang, F; Yang, W; Jiang, T; Lu, G; He, B; Li, X; Hu, T; Chen, G; Feng, Y; Zhang, Y; Fan, Q; Feng, J; Zhang, H; Tu, C (February 2016). "Detection and characterization of diverse alpha- and betacoronaviruses from bats in China". Virologica Sinica. 31 (1): 69–77. doi:10.1007/s12250-016-3727-3. PMC 7090707. PMID 26847648.69-77&rft.date=2016-02&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090707#id-name=PMC&rft_id=info:pmid/26847648&rft_id=info:doi/10.1007/s12250-016-3727-3&rft.aulast=Xu&rft.aufirst=L&rft.au=Zhang, F&rft.au=Yang, W&rft.au=Jiang, T&rft.au=Lu, G&rft.au=He, B&rft.au=Li, X&rft.au=Hu, T&rft.au=Chen, G&rft.au=Feng, Y&rft.au=Zhang, Y&rft.au=Fan, Q&rft.au=Feng, J&rft.au=Zhang, H&rft.au=Tu, C&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090707&rfr_id=info:sid/en.wikipedia.org:16BO133" class="Z3988">
- ^ a b Li, W. (2005). "Bats Are Natural Reservoirs of SARS-Like Coronaviruses". Science. 310 (5748): 676–679. Bibcode:2005Sci...310..676L. doi:10.1126/science.1118391. ISSN 0036-8075. PMID 16195424. S2CID 2971923.676-679&rft.date=2005&rft_id=https://api.semanticscholar.org/CorpusID:2971923#id-name=S2CID&rft_id=info:bibcode/2005Sci...310..676L&rft.issn=0036-8075&rft_id=info:doi/10.1126/science.1118391&rft_id=info:pmid/16195424&rft.aulast=Li&rft.aufirst=W.&rft_id=https://zenodo.org/record/3949088&rfr_id=info:sid/en.wikipedia.org:16BO133" class="Z3988">
- ^ a b Xing‐Yi Ge; Ben Hu; Zheng‐Li Shi (2015). "BAT CORONAVIRUSES". In Lin-Fa Wang; Christopher Cowled (eds.). Bats and Viruses: A New Frontier of Emerging Infectious Diseases (First ed.). John Wiley & Sons. pp. 127–155. doi:10.1002/9781118818824.ch5.127-155&rft.edition=First&rft.pub=John Wiley & Sons&rft.date=2015&rft_id=info:doi/10.1002/9781118818824.ch5&rft.au=Xing‐Yi Ge&rft.au=Ben Hu&rft.au=Zheng‐Li Shi&rfr_id=info:sid/en.wikipedia.org:16BO133" class="Z3988">
- ^ He, Biao; Zhang, Yuzhen; Xu, Lin; Yang, Weihong; Yang, Fanli; Feng, Yun; et al. (2014). "Identification of diverse alphacoronaviruses and genomic characterization of a novel severe acute respiratory syndrome-like coronavirus from bats in China". J Virol. 88 (12): 7070–82. doi:10.1128/JVI.00631-14. PMC 4054348. PMID 24719429.7070-82&rft.date=2014&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054348#id-name=PMC&rft_id=info:pmid/24719429&rft_id=info:doi/10.1128/JVI.00631-14&rft.aulast=He&rft.aufirst=Biao&rft.au=Zhang, Yuzhen&rft.au=Xu, Lin&rft.au=Yang, Weihong&rft.au=Yang, Fanli&rft.au=Feng, Yun&rft.au=Xia, Lele&rft.au=Zhou, Jihua&rft.au=Zhen, Weibin&rft.au=Feng, Ye&rft.au=Guo, Huancheng&rft.au=Zhang, Hailin&rft.au=Tu, Changchun&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054348&rfr_id=info:sid/en.wikipedia.org:16BO133" class="Z3988">
- ^ a b Lau, Susanna K. P.; Feng, Yun; Chen, Honglin; Luk, Hayes K. H.; Yang, Wei-Hong; Li, Kenneth S. M.; Zhang, Yu-Zhen; Huang, Yi; et al. (2015). "Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination". Journal of Virology. 89 (20): 10532–10547. doi:10.1128/JVI.01048-15. ISSN 0022-538X. PMC 4580176. PMID 26269185.10532-10547&rft.date=2015&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580176#id-name=PMC&rft.issn=0022-538X&rft_id=info:pmid/26269185&rft_id=info:doi/10.1128/JVI.01048-15&rft.aulast=Lau&rft.aufirst=Susanna K. P.&rft.au=Feng, Yun&rft.au=Chen, Honglin&rft.au=Luk, Hayes K. H.&rft.au=Yang, Wei-Hong&rft.au=Li, Kenneth S. M.&rft.au=Zhang, Yu-Zhen&rft.au=Huang, Yi&rft.au=Song, Zhi-Zhong&rft.au=Chow, Wang-Ngai&rft.au=Fan, Rachel Y. Y.&rft.au=Ahmed, Syed Shakeel&rft.au=Yeung, Hazel C.&rft.au=Lam, Carol S. F.&rft.au=Cai, Jian-Piao&rft.au=Wong, Samson S. Y.&rft.au=Chan, Jasper F. W.&rft.au=Yuen, Kwok-Yung&rft.au=Zhang, Hai-Lin&rft.au=Woo, Patrick C. Y.&rft.au=Perlman, S.&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580176&rfr_id=info:sid/en.wikipedia.org:16BO133" class="Z3988">
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- ^ Yang, Xing-Lou; Hu, Ben; Wang, Bo; Wang, Mei-Niang; Zhang, Qian; Zhang, Wei; et al. (2016). "Isolation and Characterization of a Novel Bat Coronavirus Closely Related to the Direct Progenitor of Severe Acute Respiratory Syndrome Coronavirus". Journal of Virology. 90 (6): 3253–6. doi:10.1128/JVI.02582-15. PMC 4810638. PMID 26719272.3253-6&rft.date=2016&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810638#id-name=PMC&rft_id=info:pmid/26719272&rft_id=info:doi/10.1128/JVI.02582-15&rft.aulast=Yang&rft.aufirst=Xing-Lou&rft.au=Hu, Ben&rft.au=Wang, Bo&rft.au=Wang, Mei-Niang&rft.au=Zhang, Qian&rft.au=Zhang, Wei&rft.au=Wu, Li-Jun&rft.au=Ge, Xing-Yi&rft.au=Zhang, Yun-Zhi&rft.au=Daszak, Peter&rft.au=Wang, Lin-Fa&rft.au=Shi, Zheng-Li&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810638&rfr_id=info:sid/en.wikipedia.org:16BO133" class="Z3988">
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Data related to 16BO133 at Wikispecies
