The enzyme (−)-endo-Fenchol synthase (EC 4.2.3.10) catalyzes the chemical reaction
| (−)-endo-fenchol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.10 | ||||||||
| CAS no. | 117758-41-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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- geranyl diphosphate H2O (−)-endo-fenchol diphosphate
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase [cyclizing, (−)-endo-fenchol-forming]. Other names in common use include (−)-endo-fenchol cyclase, and geranyl pyrophosphate:(−)-endo-fenchol cyclase. This enzyme participates in monoterpenoid biosynthesis.
References
edit- Croteau R, Miyazaki JH, Wheeler CJ (1989). "Monoterpene biosynthesis: mechanistic evaluation of the geranyl pyrophosphate:(−)-endo-fenchol cyclase from fennel (Foeniculum vulgare)". Arch. Biochem. Biophys. 269 (2): 507–16. doi:10.1016/0003-9861(89)90134-3. PMID 2919880.507-16&rft.date=1989&rft_id=info:doi/10.1016/0003-9861(89)90134-3&rft_id=info:pmid/2919880&rft.aulast=Croteau&rft.aufirst=R&rft.au=Miyazaki, JH&rft.au=Wheeler, CJ&rfr_id=info:sid/en.wikipedia.org:(−)-endo-fenchol synthase" class="Z3988">
- Croteau R, Satterwhite DM, Wheeler CJ, Felton NM (1988). "Biosynthesis of monoterpenes. Stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (−)-endo-fenchol". J. Biol. Chem. 263 (30): 15449–53. doi:10.1016/S0021-9258(19)37609-4. PMID 3170591.15449-53&rft.date=1988&rft_id=info:doi/10.1016/S0021-9258(19)37609-4&rft_id=info:pmid/3170591&rft.aulast=Croteau&rft.aufirst=R&rft.au=Satterwhite, DM&rft.au=Wheeler, CJ&rft.au=Felton, NM&rft_id=https://doi.org/10.1016%2FS0021-9258%2819%2937609-4&rfr_id=info:sid/en.wikipedia.org:(−)-endo-fenchol synthase" class="Z3988">
