( )-Sativene synthase (EC 4.2.3.129, cop4) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, ( )-sativene-forming).[1][2][3] This enzyme catalyses the following chemical reaction
| ( )-sativene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.129 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate ( )-sativene diphosphate
This enzyme is isolated from the fungus Coprinus cinereus.
References
edit- ^ Agger S, Lopez-Gallego F, Schmidt-Dannert C (June 2009). "Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus". Molecular Microbiology. 72 (5): 1181–95. doi:10.1111/j.1365-2958.2009.06717.x. PMC 2723806. PMID 19400802.1181-95&rft.date=2009-06&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723806#id-name=PMC&rft_id=info:pmid/19400802&rft_id=info:doi/10.1111/j.1365-2958.2009.06717.x&rft.aulast=Agger&rft.aufirst=S&rft.au=Lopez-Gallego, F&rft.au=Schmidt-Dannert, C&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723806&rfr_id=info:sid/en.wikipedia.org:(+)-sativene synthase" class="Z3988">
- ^ Lopez-Gallego F, Agger SA, Abate-Pella D, Distefano MD, Schmidt-Dannert C (May 2010). "Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers". ChemBioChem. 11 (8): 1093–106. doi:10.1002/cbic.200900671. PMC 2873112. PMID 20419721.1093-106&rft.date=2010-05&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873112#id-name=PMC&rft_id=info:pmid/20419721&rft_id=info:doi/10.1002/cbic.200900671&rft.aulast=Lopez-Gallego&rft.aufirst=F&rft.au=Agger, SA&rft.au=Abate-Pella, D&rft.au=Distefano, MD&rft.au=Schmidt-Dannert, C&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873112&rfr_id=info:sid/en.wikipedia.org:(+)-sativene synthase" class="Z3988">
- ^ López-Gallego F, Wawrzyn GT, Schmidt-Dannert C (December 2010). "Selectivity of fungal sesquiterpene synthases: role of the active site's H-1α loop in catalysis". Applied and Environmental Microbiology. 76 (23): 7723–33. Bibcode:2010ApEnM..76.7723L. doi:10.1128/aem.01811-10. PMC 2988597. PMID 20889795.7723-33&rft.date=2010-12&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988597#id-name=PMC&rft_id=info:pmid/20889795&rft_id=info:doi/10.1128/aem.01811-10&rft_id=info:bibcode/2010ApEnM..76.7723L&rft.aulast=López-Gallego&rft.aufirst=F&rft.au=Wawrzyn, GT&rft.au=Schmidt-Dannert, C&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988597&rfr_id=info:sid/en.wikipedia.org:(+)-sativene synthase" class="Z3988">
External links
edit- ( )-sativene synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
