Curation Scientist Step II

About Fulgent

Founded in 2011, Fulgent has evolved into a premier, full-service genomic testing company built around a foundational technology platform.

Through our diverse testing menu, Fulgent is focused on transforming patient care in oncology, anatomic pathology, infectious and rare diseases, and reproductive health. We believe that by providing a wide range of effective, flexible testing options in conjunction with best-in-class service and support, we can redefine the way medicine is managed for patients and clinicians alike.

Since integrating with our therapeutic development business, Fulgent is also developing drug candidates for treating a broad range of cancers using a novel nanoencapsulation and targeted therapy platform. By merging our fields of expertise, we aim to become a fully integrated precision medicine company.

Summary Of Position

This is the second step of the Genetic Curation Scientist (GCS) career track. Compared to Step 1, the GCS Step 2 has more responsibilities in research & development, performing del/dup analysis, and curating more complex case types such as large panels, exomes, etc. approved by a laboratory director

The GCS will be responsible for the classification of genetic variants following the ACMG guidelines (PMID: 25741868) and using a combination of internal proprietary software, published scientific literature, and publicly available databases. The GCS will determine the pathogenicity of DNA sequence variants found in real-time in patients and will customize clinical report text in collaboration with laboratory directors and genetic counselors. The GCS is also responsible for quality control, technical assessment, copy number analysis, and other interpretive components of molecular diagnostics as outlined in the curation standard operating procedures.

KEY JOB ELEMENTS

• Perform quality control assessment for Next Generation Sequencing and other molecular diagnostic assays.
• Must be approved to perform del/dup analysis (“First Check”).
• Must be approved to perform large panel and/or exome sequencing curation.
• Classify detected variants according to internal and professional guidelines.
• Draft clinical lab reports according to internal and professional standards; reports will be submitted to a laboratory director for final review and sign-out.
• Review literature and databases to evaluate gene-disease association.
• Review and update genetic variations based on new information.
• Support Client Services Department and Laboratory Genetic Counselors to respond to client requests for information on the interpretation of variants.
• Participate in research & development projects as they arise.
  
  

Knowledge / Experience

Preferred Experiences

• Proven ability to critically read and interpret scientific literature.
• Strong computer, scientific, and organizational skills.
• Outstanding attention to detail and efficient work habits.
• Excellent communication (oral and written).
• Ability to work independently and as part of a team with self-motivation, adaptability, and a positive attitude.
• Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.
  
  

Minimum Qualifications

• Ph.D. in Human Genetics or an appropriately related field, with a strong molecular genetics background or previous DNA sequencing reporting experience.
• Familiarity with Mendelian genetics and a thorough knowledge of molecular genetics.
• 1 year of experience as a GCS at Fulgent or equivalent experience at a different institution.
  
  

Supervisory Responsibilities

• None
  
  

REPORTS TO

• Laboratory Director
  
  

ENVIRONMENT

Fulgent Therapeutics LLC is an Equal Employment Opportunity Employer.

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions. The term “qualified individual with a disability” means an individual with a disability who, with or without reasonable accommodation, can perform the essential functions of the position.

Safety And Work Environment

• General office environment. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
• Maintains a clean, neat, and orderly work area.
• Adheres to Department Specific Safety Guidelines.
  
  

Physical Demands

• Standing, sitting, walking, bending, reaching, manual manipulation, and lifting up to 10 pounds.
  
  

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CCPA Privacy Notice for California Residents

https://tinyurl.com/FulgentCCPA