NFYB

NFYB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1N1J, 4AWL, 4CSR
Dynodwyr
Cyfenwau	NFYB, CBF-A, CBF-B, HAP3, NF-YB, nuclear transcription factor Y subunit beta
Dynodwyr allanol	OMIM: 189904 HomoloGene: 38149 GeneCards: NFYB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • DNA binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0032403 protein-containing complex binding Cydrannau o'r gell • protein-DNA complex • nucleoplasm • CCAAT-binding factor complex • cnewyllyn cell • RNA polymerase II transcription regulator complex Prosesau biolegol • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • regulation of cholesterol biosynthetic process • cellular response to leukemia inhibitory factor • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1950094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4801	n/a
Ensembl	ENSG00000120837	n/a
UniProt	P25208	n/a
RefSeq (mRNA)	NM_006166	n/a
RefSeq (protein)	NP_006157 NP_006157.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NFYB yw NFYB a elwir hefyd yn Nuclear transcription factor Y subunit beta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NFYB.

• HAP3
• CBF-A
• CBF-B
• NF-YB

Llyfryddiaeth

• "NF-Y is associated with the histone acetyltransferases GCN5 and P/CAF. ". J Biol Chem. 1998. PMID 9430679.
• "Physical and functional interaction between the human T-cell lymphotropic virus type 1 Tax1 protein and the CCAAT binding protein NF-Y. ". Mol Cell Biol. 1997. PMID 9032250.
• "Human thymidine kinase CCAAT-binding protein is NF-Y, whose A subunit expression is serum-dependent in human IMR-90 diploid fibroblasts. ". J Biol Chem. 1994. PMID 8027044.
• "NF-Y activates genes of metabolic pathways altered in cancer cells. ". Oncotarget. 2016. PMID 26646448.
• "E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program.". PLoS One. 2015. PMID 26039627.